Show simple item record

dc.contributor.authorRosales-Rimache, Jaimees_ES
dc.contributor.authorChavez-Ruiz, Manueles_ES
dc.contributor.authorInolopú-Cucche, Jorgees_ES
dc.contributor.authorRabanal-Sanchez, Jhonatanes_ES
dc.contributor.authorRueda-Torres, Lenines_ES
dc.contributor.authorSanchez-Holguin, Gloriaes_ES
dc.date.accessioned2022-10-25T15:20:31Z
dc.date.available2022-10-25T15:20:31Z
dc.date.issued2022-05-30
dc.identifier.urihttps://hdl.handle.net/20.500.13053/6925
dc.description.abstractPeru is one of the countries with the highest leadcontamination in the world. Biological monitoring has lim-itations due to the shortage of laboratories with validatedmethodologies for the measurement of blood lead, and it isnecessary to use alternative methods for its measurement inhigh-altitude cities. We aimed to compare the blood leadlevels (BLL) measured by the LeadCare II (LC) method andGraphite Furnace Atomic Absorption Spectrometry (GF-AAS). We measured the BLL of 108 children from the city ofLa Oroya. The mean and median BLL for GF-AAS were10.77±4.18 and 10.44lg/dL, respectively; for the LCmethod, the mean was 11.71±4.28 and the median was11.60lg/dL. We found a positive linear correlation(Rho = 0.923) between both methods. Notwithstanding, theWilcoxon test suggests a significant difference between bothmethods (q= 0.000). In addition, the Bland–Altmananalysis indicates that there is a positive bias (0.94) in the LCmethod, and this method tends to overestimate the BLL.Likewise, we performed a generalized linear model toevaluate the influence of age and hemoglobin on BLL. Wefound that age and hemoglobin had a significant influence onBLL measured by the LC method. Finally, we used two non-parametric linear regression methods (Deming and Passing-Bablok regression) to compare the LC method with the GF-AAS. We found that these methods differ by at least a con-stant amount, and there would be a proportional differencebetween both. Although in general there is a positive linearcorrelation, the results of both methods differ significantly.Therefore, its use in cities located at high altitudes (higherthan 2440 m.a.s.l.) would not be recommended.es_ES
dc.formatapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_ES
dc.subjectLeadCare Blood Lead Graphite FurnaceAtomic Absorption Spectrometryes_ES
dc.titleLeadcare II Comparison with Graphite Furnace AtomicAbsorption Spectrophotometry for Blood Lead Measurementin Peruvian Highlandses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doihttps://doi.org/10.1007/s12291-022-01050-yes_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
dc.publisher.countryINes_ES
dc.subject.ocdehttp://purl.org/pe-repo/ocde/ford#3.03.00es_ES


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/openAccess
Except where otherwise noted, this item's license is described as info:eu-repo/semantics/openAccess