A Functional Assessment Tool to Distinguish Controls From Alzheimer’s Disease in Lima, Peru

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dc.contributor.author Custodio, Nilton es_ES
dc.contributor.author Montesinos, Rosa es_ES
dc.contributor.author Chambergo-Michilot, Diego es_ES
dc.contributor.author Herrera-Perez, Eder es_ES
dc.contributor.author Pintado-Caipa, Maritza es_ES
dc.contributor.author Seminario, Wendy es_ES
dc.contributor.author Cuenca, Jose es_ES
dc.contributor.author Mesía, Laura es_ES
dc.contributor.author Failoc-Rojas, Virgilio E es_ES
dc.contributor.author Diaz, Monica M es_ES
dc.date.accessioned 2022-11-08T16:59:07Z
dc.date.available 2022-11-08T16:59:07Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.13053/7019
dc.description.abstract Background: The Alzheimer’s Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functional assessment tool for patients with Alzheimer’s disease (AD). We evaluated its performance in controls, Peruvians with MCI or AD. Methods: A cross-sectional study of older adults attending a neurology institute in Lima (Peru) with mild cognitive impairment (MCI), AD or cognitively healthy. Test-retest reliability (intraclass correlation coefficient, ICC; internal consistency, Cronbach’s alpha) and validity were assessed. Results: We enrolled 276 individuals (AD: 113, MCI: 68, controls: 95) with no age, sex, educational level, and depressive symptom differences. Reliability was ideal (ICC: .996), and Cronbach’s alpha was adequate (.937). The ADCS-ADL could not differentiate MCI from controls but did differentiate AD severity. The ADCS-ADL correlated highly with nearly all tools. Conclusions: The ADCS-ADL scale is reliable in a population with AD in Lima, Peru. Future work may validate a tool for Peruvians with lower educational levels. es_ES
dc.format application/pdf es_ES
dc.language.iso eng es_ES
dc.rights info:eu-repo/semantics/openAccess es_ES
dc.rights.uri https://creativecommons.org/licenses/by/4.0/ es_ES
dc.subject alzheimer disease, dementia, neurocognitive disorders, peru, validation study es_ES
dc.title A Functional Assessment Tool to Distinguish Controls From Alzheimer’s Disease in Lima, Peru es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.identifier.doi https://doi.org/10.1177/15333175221104354 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.subject.ocde http://purl.org/pe-repo/ocde/ford#3.03.00 es_ES

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