Risk factors for in-hospital complications in patients with acute ischemic stroke: Retrospective cohort in a national reference hospital in Peru
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Date
2023-04-26Author(s)
Vences, Miguel A
Failoc-Rojas, Virgilio E
Urrunaga-Pastor, Diego
Hurtado-Roca, Yamilée
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Show full item recordAbstract
Objective: To describe the clinical and demographic characteristics of patients with acute cerebral
infarction treated at a national reference hospital in Peru and determine the risk factors for inhospital complications.
Methods: We conducted a retrospective cohort study including 192 patients with acute ischemic
stroke in a national reference hospital in Peru from January to September 2021. Clinical, demographic and paraclinical information was recorded from medical records. We estimated risk
ratios and 95% confidence intervals using regression models with Poisson family and robust
variance for the bivariate and multivariate model, adjusting for age, sex and risk factors for
stroke.
Results: At least one in-hospital complication occurred in 32.3% of the patients. The most frequent
complications were infectious in 22.4%, followed by 17.7% of neurological complications, with
other complications, such as thromboembolism, immobility and miscellaneous, being much less
frequent. Regression analysis showed that stroke severity (RR = 1.76; 95%CI:1.09–2.86) and
albumin greater than 3.5 mg/dL (RR = 0.53; 95%CI: 0.36–0.79) were independent risk factors for
the presence of in-hospital complications.
Conclusions: A high rate of in-hospital complications were observed, among which infectious and
neurological complications were the most frequent. Stroke severity was a risk factor and albumin
greater than 3.5 mg/dL was a protective factor for the incidence of in-hospital complications.
These results can serve as a starting point for establishing stroke care systems that consider
differentiated flows for the prevention of in-hospital complications.
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