Bardelli, María LuisaNeciosup-Leon, MarycieloCastilla-Espinoza, Carlos S.Torres-Pesantes, LucianaRodrigo-Gallardo, Paola K.Huamanchumo-Suyon, Medalit E.Bendezu-Quispe, GuidoSalinas-Sedo, GustavoToro-Huamanchumo, Carlos J.2023-08-012023-08-012023-03-15https://hdl.handle.net/20.500.13053/9102“Objective: To assess the association between the percentage of excess body mass index loss (%EBMIL) and cardiometabolic risk reduction in Peruvian adults undergoing laparoscopic sleeve gastrectomy (LSG). Methods: Retrospective cohort study conducted with adult patients who underwent LSG in a bariatric clinic during 2016–2020. The outcome variable was cardiometabolic risk change (expressed in Δ) 1 year after LSG. To that effect, the variables total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein (LDL) cholesterol, very LDL (VLDL) cholesterol, triglycerides, glucose, insulin, and HOMA-IR at baseline and after 12 months were considered. The exposure variable was %EBMIL. Crude and adjusted β coefficients were estimated with linear regression models. Results: Of the 110 patients analyzed, 68.2% were women, and the median patient age was 34.5 years. In the model adjusted for sex, age, and baseline BMI, we noted that each 25% increase in %EBMIL resulted in a decrease in the values for total cholesterol, LDL, triglycerides, and insulin by 10.36 mg/dL (p < 0.001), 7.98 mg/dL (p = 0.001), 13.35 mg/dL (p = 0.033), and 3.63 uU/mL (p = 0.040), respectively. Conclusion: %EBMIL was associated with a decrease in total cholesterol, LDL, triglycerides, and insulin levels, which could suggest a favorable cardiometabolic evolution during the first 12 months following LSG.“application/pdfenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/"Body mass index Metabolic syndrome Cardiovascular diseases Bariatric surgery Peru "info:eu-repo/semantics/article10.1016/j.obmed.2023.1004883.00.00 -- Ciencias médicas, Ciencias de la salud