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dc.contributor.authorMillones Gómez, Pablo Alejandroes_ES
dc.contributor.authorRequena Mendizábal, Margarita Fees_ES
dc.contributor.authorCalla Poma, Roger Damasoes_ES
dc.contributor.authorRosales Cifuentes, Tania Valentinaes_ES
dc.contributor.authorMalpartida Quispe, Federico Martines_ES
dc.contributor.authorMaurtua Torres, Dora Jesúses_ES
dc.contributor.authorBacilio Amaranto, Reyma Evelynes_ES
dc.contributor.authorMinchón Medina, Carlos Albertoes_ES
dc.contributor.authorPonce Contreras, Lusin Antonioes_ES
dc.date.accessioned2022-10-21T16:51:13Z
dc.date.available2022-10-21T16:51:13Z
dc.date.issued2022-05-16
dc.identifier.urihttps://hdl.handle.net/20.500.13053/6895
dc.description.abstractObjective:To assess the antibacterial activity of Psidium guajavafractions and their effects on adhesion of a multispecies biofilm consisting of Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalisin vitro. Material and Methods:Guava leaves were obtained from the mountains of northern Peru, where they grow wild and free of pesticides. The antimicrobial activity of 25 mg/mL petroleum ether, 25 mg/mL dichloromethane and 25 mg/mL methanol fractions of P. guajavawas evaluated by measuring inhibition halos, as well as the effect on the adhesion of multispecies biofilms at 4, 7 and 10 days of growth by measuring the optical density. In addition, antimicrobialsusceptibility was compared using the Kruskal-Wallis test and its multiple comparison tests, and differences in mean biofilm adhesion between each fraction were assessed by repeated measures analysis and the Tukey multiple comparison test.Results:The rank-based Kruskal-Wallis test highlighted differences in the effects of the fractions on the zone of inhibition for each oral bacterium, including S. gordonii(p=0.000), F. nucleatum(p=0.000), and P. gingivalis(p=0.000), the Tukey test showed that the group treated with 0.12% chlorhexidine exhibited the least amount of adhesion, followed by the group treated with the 1.56 mg/mL methanol fraction. Conclusion:The methanol fraction of P. guajavahad an antibacterial effect on S. gordoniiand P. gingivalis, and the 1.56 mg/mL methanol fraction decreased biofilm adhesion.es_ES
dc.formatapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherAssociation of Support to Oral Health Research (APESB)es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_ES
dc.subjectPsidium; Biofilms; Gram-Negative Bacteria.es_ES
dc.titleAntibacterial and Antiadhesion Effects of Psidium guajavaFractions on aMultispecies Biofilm Associated with Periodontitises_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doihttps://doi.org/10.1590/pboci.2022.028es_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
dc.publisher.countryBRes_ES
dc.subject.ocdehttp://purl.org/pe-repo/ocde/ford#3.03.00es_ES


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