“Percentage of excess body mass index loss and cardiometabolic risk reduction in Peruvian adults undergoing sleeve gastrectomy“
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Fecha
2023-03-15Autor(es)
Bardelli, María Luisa
Neciosup-Leon, Marycielo
Castilla-Espinoza, Carlos S.
Torres-Pesantes, Luciana
Rodrigo-Gallardo, Paola K.
Huamanchumo-Suyon, Medalit E.
Bendezu-Quispe, Guido
Salinas-Sedo, Gustavo
Toro-Huamanchumo, Carlos J.
Metadatos
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“Objective: To assess the association between the percentage of excess body mass index loss
(%EBMIL) and cardiometabolic risk reduction in Peruvian adults undergoing laparoscopic sleeve
gastrectomy (LSG).
Methods: Retrospective cohort study conducted with adult patients who underwent LSG in a
bariatric clinic during 2016–2020. The outcome variable was cardiometabolic risk change (expressed in Δ) 1 year after LSG. To that effect, the variables total cholesterol, high-density
lipoprotein cholesterol, low-density lipoprotein (LDL) cholesterol, very LDL (VLDL) cholesterol,
triglycerides, glucose, insulin, and HOMA-IR at baseline and after 12 months were considered.
The exposure variable was %EBMIL. Crude and adjusted β coefficients were estimated with linear regression models.
Results: Of the 110 patients analyzed, 68.2% were women, and the median patient age was 34.5
years. In the model adjusted for sex, age, and baseline BMI, we noted that each 25% increase in
%EBMIL resulted in a decrease in the values for total cholesterol, LDL, triglycerides, and insulin
by 10.36 mg/dL (p < 0.001), 7.98 mg/dL (p = 0.001), 13.35 mg/dL (p = 0.033), and 3.63
uU/mL (p = 0.040), respectively.
Conclusion: %EBMIL was associated with a decrease in total cholesterol, LDL, triglycerides, and
insulin levels, which could suggest a favorable cardiometabolic evolution during the first 12
months following LSG.“
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