Farmacia y Bioquímica

URI permanente para esta comunidadhttps://hdl.handle.net/20.500.13053/33

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Examinando Farmacia y Bioquímica por Autor "Abarca Heredia, Mercy Yoseli"

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    Prescripción y consumo de antibióticos de reserva en los servicios de hospitalización de la Clínica Internacional, enero–junio 2014
    (Universidad Privada Norbert Wiener, 2015) Abarca Heredia, Mercy Yoseli; Paulino Anglas, Ronald; Caldas Herrera, Emma
    Introduction: The inappropriate use of reserve antibiotics results in the generation of resistant microorganisms, leading to longer hospital stays and higher healthcare costs. Objective: To determine the prescription and consumption of reserve antibiotics in the hospitalization services of the Clínica Internacional, January – June 2014. Methodology: Observational and retrospective drug utilization study in a sample of 237 patients. The information was collected from medical records using a data collection form. The consumption of antibiotics was expressed in DDD/100 bed-days. Results: The most frequently prescribed reserve antibiotic was Ceftriaxone (66.90%), followed by Vancomycin (7.93%); with Internal Medicine specialists (22.40%) and Oncological Surgery (17.60%) prescribing these types of antibacterials most frequently. The most common diagnoses were: urinary tract infections (13.50%), cellulitis (5.06%), and sepsis (3.80%). In 43.46% of the diagnoses, Ceftriaxone was used as surgical prophylaxis. The selection of reserve antibiotics was consistent with the Guideline for the Treatment of Infectious Diseases 2013–2014 PAHO – WHO in 40.69% of cases. A total of 35.17% of interconsultations were carried out with the Infectology service, and 28.62% of prescribed antibiotics were authorized. Culture testing was requested in 33% of patients. Finally, the reserve antibiotic with the highest consumption was Ceftriaxone with 5.98 DDD/100 bed-days. Conclusion: The prescription of reserve antibiotics occurred mostly without microbiological support and without prior authorization by the Infectology service. Ceftriaxone is the most prescribed and consumed reserve antibiotic, generally used in surgical prophylaxis. This reflects the need for the creation of clinical guidelines and compliance with policies aimed at the rational use of antibacterials.