Examinando por Autor "Anco Maximiliano, Yanet Soleda"

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  • Miniatura
    PublicaciónAcceso abierto
    Actitud hacia la investigación y el pensamiento crítico en los estudiantes de Farmacia y Bioquímica de una universidad privada, 2021
    (Universidad Privada Norbert Wiener, 2023-01-31) Anco Maximiliano, Yanet Soleda; Palacios Garay, Jessica Paola
    Research today is considered one of the most important jobs for every professional because it forces the person to have critical thinking, generating new knowledge for its application according to the different needs, that is why the initiative for the development of this study with the objective of being able to determine the relationship that exists between the attitude towards research and critical thinking in the students of a private university, 2021. The methodological design was with a substantive quantitative approach and a correlational descriptive level, the results obtained were that there is a significant relationship between the attitude towards research and critical thinking in the students of Pharmacy and Biochemistry of a private university, 2021. Finally, it is concluded that the level of attitude of the students of the Faculty of Pharmacy and Biochemistry of Attitude towards research and critical thinking in pharmacy and biochemistry students a from a private university, 2021, is high, that is, out of 120 students surveyed, 74 of them, which is equivalent to 61.7%, consider that patience and curiosity for most of the things they analyze are key elements that reinforce their attitude towards research.
  • Miniatura
    PublicaciónAcceso abierto
    Actividad anticonvulsivante del extracto hidroalcoholico de raíz de Valeriana pinnatifida R. & P. "Valeriana"
    (Universidad Privada Norbert Wiener, 2018-11-24) Anco Maximiliano, Yanet Soleda; Chávez Fernández, Ana María
    Valeriana pinnatifida is a native plant of the Valerianaceae family, endemic to Peru, which grows on rocky slopes in the Andes. Traditionally, it has been used as a sedative, hypnotic, and tranquilizer. This study was initiated to analyze the metabolites present in the plant, determine its acute toxicity, and evaluate its anticonvulsant effect. The research was quasi-experimental. For the phytochemical study, a hydroalcoholic extract was obtained from the root of Valeriana pinnatifida R. & P., "valeriana," via maceration. Acute toxicity was determined at a limit dose of 2000 mg/kg using the OECD 423 protocol. The anticonvulsant effect was evaluated using an experimental model of pentylenetetrazol (PTZ)-induced seizures in mice. Five groups of six albino mice of the C53/CNPB strain were used: group 1 (saline control), group 2 (PTZ 80mg/kg), group 3 (diazepam 5mg/kg + PTZ), group 4 (EHVP 300mg/kg + PTZ), and group 5 (EHVP 400mg/kg + PTZ). The treatments were administered orally 30 minutes before the induction of seizures with PTZ. The results identified the secondary metabolites alkaloids and terpenes. The toxicity study showed a significant variation in the weight of the mice. The 300 mg/kg dose demonstrated a statistically significant anticonvulsant activity compared to the control group in terms of seizure severity and mortality. It is concluded that the hydroalcoholic root extract of Valeriana pinnatifida R. & P., "valeriana," at a concentration of 300 mg/kg, exhibits an anticonvulsant effect.