Examinando por Autor "Basilio Córdova, Deisy Sumiela"

Seleccione resultados tecleando las primeras letras
Mostrando 1 - 1 de 1
  • Miniatura
    ÍtemAcceso abierto
    Comparative analysis of the performance of two automated hematological platforms in a level III-I Hospital of the MINSA-Peru in 2023
    (Universidad Privada Norbert Wiener, 2024-06-09) Basilio Córdova, Deisy Sumiela; Huamán Cárdenas, Victor Raul
    Objective: To compare the analytical performance of the two hematological platforms Beckman Coulter DxH 900 and Mindray BC 6200 used in a level III-I Hospital in Minsa-Peru 2023. Materials and Methods: Based on the CLSI EP15-A3(1) guide, 5 replicates will be performed for each control level over 5 consecutive days, totaling 25 runs per level for leukocytes, erythrocytes, hemoglobin, and platelets. Based on the CLSI EP6-A(2) guide, 5 samples with equidistant concentrations will be tested 3 times for leukocytes and platelets. Results: On the Beckman Coulter DxH900 platform, the Sigma values are 10.9 for leukocytes, 4.6 for erythrocytes, 5.3 for hemoglobin, and 8.1 for platelets. The results for %CVWL(Lab) were lower than the %CVWL(Fab), thus the verification is accepted for each analyte. The overall precision determination for each analyte was based on the limiting level, so the imprecision is 1.5 for leukocytes, 0.8 for erythrocytes, 0.6 for hemoglobin, and 1.6 for platelets. For the Mindray BC6200 platform, the Sigma values are 6.5 for leukocytes, 8.5 for erythrocytes, 7.4 for hemoglobin, and 4.6 for platelets. The %CVWL(Lab) results were lower than the %CVWL(Fab), so the verification is accepted for each analyte. However, the %CVR(Lab) for platelets was rejected at level 1 because it exceeded the %CVR(Fab) and accepted for other levels, but the intralaboratory condition is considered acceptable. The overall precision determination for each analyte was based on the limiting level, with imprecision of 1.6 for leukocytes, 0.7 for erythrocytes, 0.3 for hemoglobin, and 4.8 for platelets. Conclusions: Both platforms met the manufacturer's accuracy and precision specifications, with a favorable Sigma, considering that both platforms worked with the same short quality requirement (VBD). The Beckman platform performed better compared to the Mindray platform.