Examinando por Autor "Bruno Mingore, Corina Isabel"

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    Evaluación del efecto gastroprotector del extracto etanólico de las hojas de Alternanthera lanceolata (Benth.) Schinz. “lancetilla” en ratas Holtzman
    (Universidad Privada Norbert Wiener, 2022-08-25) Bruno Mingore, Corina Isabel; Chuquiyauri Rua, Roxana; Chávez Flores, Juana Elvira
    Peru is a country with vast biodiversity, featuring diverse flora resources to meet human needs; medicinal plants are capable of treating and curing certain human diseases and ailments worldwide. Objective: To evaluate the gastroprotective effect of the ethanolic extract from the leaves of Alternanthera lanceolata (Benth) Schinz, 'Lancetilla,' in rats. Methodology: Albino rats were used, divided randomly into 6 groups of 8 animals each. The gastroprotective effect was determined using the Lee method with the Marhuenda scale for evaluation, and an anatomopathological section analysis was also performed. Results: The ethanolic extract from the leaves of Alternanthera lanceolata at a concentration of 600 mg/kg presented the highest gastroprotective effect, obtaining 45.19% mucosal loss, compared to the Ranitidine 300 mg/kg standard, which obtained 50.38% mucosal loss. The anatomopathological sections confirmed the gastroprotective effect by showing only a lesion grade of 1. Conclusion: The gastroprotective effect of the ethanolic extract from the leaves of Alternanthera lanceolata (Benth) Schinz, 'Lancetilla,' at a concentration of 600 mg/kg was confirmed.