Examinando por Autor "Cabanillas Mejía, Jesús José"

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    Polifarmacia e interacciones farmacológicas en adultos mayores atendidos en el departamento de medicina del Hospital Militar Central Coronel Arias Schreiber, Lima 2024
    (Universidad Privada Norbert Wiener, 2025-06-02) Arce Tarazona, Soreli Soledad; Cabanillas Mejía, Jesús José; Muñoz Jáuregui, Manuel Jesús
    The present work had the objective: "To determine the relationship between polypharmacy and drug-drug interactions in older adults treated in the Department of Medicine of the Coronel Arias Schreiber Central Military Hospital, Lima 2024". Being the methodology, this basic research was based on the quantitative approach and the hypothetical-deductive method. Its methodological design corresponded to a non-experimental and retrospective study with cross-sectional and correlational level, the population object of analysis consisted of 130 Pharmacotherapeutic Monitoring Forms. To obtain the results, the Cramer's V statistical test was used, obtaining the following: It shows that there are a greater number of pharmacotherapeutic monitoring forms with patients in the age range of 60 to 70 years (36.9%) and that the most present sex was male with 71.5%. Regarding polypharmacy, more patients were found to have excessive polypharmacy, at 74.6%. On the other hand, regarding the drug-drug interactions dimension based on severity, the highest severity was found, at 71.5%. Regarding the level of documentation dimension, the moderate level was most prevalent, at 76.9%. In the interaction mechanism dimension, pharmacodynamic interactions were more common in older adults than pharmacokinetic interactions (54.6% vs. 45.4%). Regarding hypothesis testing, the relationship and high intensity of the association between the polypharmacy variable and the drug-drug interactions variable were confirmed, with a p-value of 0.000 < 0.05 and a Cramer's V value of 0.776 (greater than 1). It was concluded that there was a correlation between polypharmacy and drug-drug interactions in older adults.