Examinando por Autor "Carlos Musayon, Jessica Viviana"

Seleccione resultados tecleando las primeras letras
Mostrando 1 - 1 de 1
  • Miniatura
    ÍtemAcceso abierto
    Antipyretic efficacy of combined versus individual use of acetaminophen and ibuprofen in febrile pediatric patients.
    (Universidad Privada Norbert Wiener, 2018-03-25) Carlos Musayon, Jessica Viviana; Casanova Taya, Betty; Matta Solis, Hernan Hugo
    Objective: To systematically analyze the evidence of the combined use of paracetamol and ibuprofen versus their individual use. Material and Method: The systematic review of 10 articles on the antipyretic efficacy of the combined use versus individual use of paracetamol and ibuprofen in febrile pediatric patients in the emergency department was found in the following databases: Cochrane, SciELO, Medline, PubMed, and Elsevier. Of the 10 articles reviewed, 60% (6/10) correspond to the methodological design of randomized clinical trials, 30% (3/10) are systematic reviews, and 10% (1/10) is a simple review. All of them were analyzed according to the GRADE scale to determine their strength and quality of evidence. Results: 80% of the reviewed articles are conclusive, supported by 1 systematic review and 1 simple review, suggesting that combined therapy is better than monotherapy, and 6 randomized clinical trials showing that the combined use of paracetamol and ibuprofen works more effectively and even faster than paracetamol or ibuprofen alone. However, the other 20% recommend that further studies in larger populations are necessary to confirm its efficacy. Conclusions: Of the 10 articles reviewed, 80% (8/10) demonstrate the efficacy of the combined use of paracetamol and ibuprofen in febrile pediatric patients.