Examinando por Autor "Carranza Trujillo, Tatiana"

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Factores de riesgo de reacciones adversas medicamentosas en niños hospitalizados en neurocirugía Instituto Nacional de Salud del Niño enero–mayo 2021
(Universidad Privada Norbert Wiener, 2021-08-12) Barrientos Mendoza, Elizabeth; Carranza Trujillo, Tatiana; Torres Veliz, Ernesto Raúl
Adverse Drug Reactions (ADRs) are a clinical problem, and drug safety in the pediatric age group is not well-established. Objective: To determine the risk factors for ADRs in children hospitalized in the neurosurgery service of the National Institute of Child Health (INSN) from January to May 2021. Methodology: The design was observational, descriptive, retrospective. The population was 101 clinical records, from which 32 cases of ADRs were identified. Data were obtained using an expert-validated data collection form and analyzed with descriptive statistics. Results: A prevalence of the female gender and the age groups of adolescents (41%) and infants (34%) was observed. Renal, cardiac, and hematological diseases were the main prevalent pathologies. Anticonvulsants (phenytoin), corticosteroids (Dexametasona), antimicrobials (Vancomycin), and antidiuretics (Desmopresina) are the therapeutic groups and drugs related to ADR risk factors in children hospitalized in the INSN neurosurgery unit. Probable ADRs predominated by causality (44%), moderate by severity (94%), and Type A or Augmented by ADR type (56%), mainly related to the previously described medications. Conclusion: The female sex, the adolescent and infant age groups, anticonvulsants, antimicrobials, and corticosteroids are the main risk factors associated with ADRs found in children hospitalized in the neurosurgery service of the National Institute of Child Health.