Examinando por Autor "Cervera Alarcon, Romy Claude"

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Critical review: effect of the use of probiotics as a supplement in patients with Alzheimer's
(Universidad Privada Norbert Wiener, 2024-07-11) Cervera Alarcon, Romy Claude; Espinoza Rado, Erika Paola
Alzheimer's AD as a pathology is a degenerative alteration of the central nervous system, which determines a loss of knowledge and reduced cognitive function. Patients with Alzheimer's are at serious risk of developing protein and energy malnutrition, which is associated with increased morbidity and mortality. Some alterations can affect the nutritional status of patients with Alzheimer's, which includes loss of autonomy, disorientation, eating disorders, weight loss and frequent ambulatory activities, and this would lead to progression in the disease. The present review aims to collect information on the use of Probiotics as a supplement in patients diagnosed with Alzheimer's. The clinical question was: What is the effect of using Probiotics through supplements in patients with Alzheimer's? An evidence-based nutrition (NuBE) approach was used. After searching databases such as PUBMED, SCIELO, SCOPUS, SCIENCE DIRECT, 13 articles were found, of which 9 were selected to be evaluated by the CASPE critical reading tool, the selected research was the Randomized Clinical Trial RCT Effect of Probiotics Bifidobacterium Breva in Improving Cognitive Function and Preventing Brain Atrophy in Elderly Patients With Suspected Mild Cognitive Impairment: Results of a Randomized, Double-Blind Study of 24 weeks (PREADVISE) which has a level of evidence AI and Grade of Recommendation I. The critical comment; This study included tests for the timely detection of mild cognitive impairment (MCI) and dementia such as ADAS-jcog and MMSE, which had a positive correlation with respect to supplementation with B. breve MCC1274 in preventing the progression of brain atrophy. After 24 weeks of supplementation, it gives us a broad overview of the nutritional intervention, this research was supported by other results; observational and prospective studies that suggest that the use of Probiotics improves mild cognitive function and the incidence of AD; Likewise, these studies are based more on the benefits of the intestinal microbiota and its relationship with mild cognitive impairment (MCI) and dementia.