Examinando por Autor "Chucas Ascencio, Luis Alberto"

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Lymphocyte indices associated with complicated appendicitis in adults in a hospital, 2021 - 2023
(Universidad Privada Norbert Wiener, 2024-08-23) Rodríguez Loloc, Kricel; Chucas Ascencio, Luis Alberto
Introduction: The need to identify accessible, quick, and low-cost markers to recognize complications in acute appendicitis leads to the study of various indices in requested blood tests. Objective: To determine the association between leukocyte indices and complicated appendicitis in adults treated at the National Hospital Edgardo Rebagliati Martins during 2021-2023. Materials and Methods: An observational analytical case-control study was conducted. The population consisted of all adult patients over 18 years old treated for acute appendicitis at the Hospital Edgardo Rebagliati Martins from 2021-2023. A sample of 171 patients was included, divided into 57 cases and 114 controls. Complicated appendicitis was the variable 2, and neutrophil, monocyte, and platelet indices were the variable 1. Data collection was performed from clinical records. Descriptive and inferential statistics were applied with a significance level of p<0.05, and the Odds Ratio (OR) was calculated in both crude and adjusted forms. Results: Of the 171 patients with acute appendicitis, the mean age was 49.7 years (SD 19.1), and 50.29% (n=86) were male. 82.46% (n=47) had an elevated neutrophil/lymphocyte ratio, 54.39% (n=31) had a low monocyte/lymphocyte ratio, and 82.46% (n=47) had an elevated platelet/lymphocyte ratio. In multivariate analysis, an association was reported for the elevated neutrophil/lymphocyte ratio (ORa: 3.5, CI: 1.52-8.05, p=0.003). Conclusions: The elevated neutrophil/lymphocyte ratio is associated with complicated appendicitis in adults.