Examinando por Autor "Chuquiyauri Carrasco, Anghela Ines"

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    Estudio comparativo de la estabilidad acelerada del paracetamol jarabe y exploración de las formulaciones de laboratorios farmacéuticos en Lima metropolitana, 2024
    (Universidad Privada Norbert Wiener, 2025-10-29) Chuquiyauri Carrasco, Anghela Ines; Tello Mestanza, Lila; Alvarado Chávez, Britt
    Objective: To determine the accelerated stability comparisons of paracetamol syrup and explore formulations from pharmaceutical laboratories in Metropolitan Lima in 2024. Methodology: A quantitative approach was used, employing deductive reasoning, an experimental design, and a cross-sectional study. The population consisted of paracetamol syrups from national and generic laboratories, with one bottle sampled per formula. The technique used was observation, supported by a data collection form. Results: The organoleptic evaluation (color, odor, taste, and absence of particles) met the parameters established in the Peruvian Technical Standard for oral medications. The physicochemical properties remained within the specified ranges: delivery volume, moisture loss (no more than 5%), pH (3.8–6.1), and density (1.000 g/mL–1.120 g/mL). Microbiological controls revealed an absence of aerobic microorganisms and fungi in all samples. Compliance with Good Storage Practices (GSP) was verified in pharmacies and drugstores, which contributed to preserving the stability, efficacy, and safety of the product throughout its shelf life. Conclusions: After determining the accelerated stability comparisons of paracetamol syrup and exploring the formulations of pharmaceutical laboratories in Metropolitan Lima in 2024, it can be stated that they comply with Peruvian technical and regulatory standards, guaranteeing a safe, effective, and high-quality product. The importance of maintaining strict quality controls and appropriate storage conditions to ensure the stability and optimal therapeutic performance of medications is emphasized.