Examinando por Autor "Cruzado Avila, Ivette Johalina"

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    Urinary Osmolality and Its Relationship with Glomerular Filtration Rate. Laboratory of the National Hospital Hipólito Unánue. Lima 2016
    (Universidad Privada Norbert Wiener, 1905-07-09) Cruzado Avila, Ivette Johalina; Sandoval Vegas, Miguel Hernán
    The objective of the study was to determine urinary osmolality and its relationship with glomerular filtration rate (GFR) using the CKD-EPI and MDRD-4 formulas in patients treated at the National Hipólito Unanue Hospital laboratory in Lima, 2016. A total of 184 urine samples meeting the inclusion criteria were selected, with 24-hour urinary osmolality measured and GFR data processed from the hospital laboratory using the Dubois and Dubois body surface area (BSA) formula. GFR was also calculated using the Mosteller and Boyd BSA formulas and the MDRD-4. Results were analyzed using Pearson’s r and Student’s t-test. No correlation was found between GFR or MDRD-4 with urinary osmolality at any stage of chronic kidney disease. A significant difference in osmolality values was observed between stage 1 (GFR >60 mL/min) and the other stages of chronic kidney disease (GFR <60 mL/min). Thus, there was no correlation between osmolality and GFR, but urinary osmolality can be used as an indicator to classify patients with adequate or decreased glomerular filtration.