Examinando por Autor "Díaz-Vélez, Cristian"

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Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis
(Elsevier Ltd, 2022-07-18) Valladares-Garrido, Mario J.; Failoc-Rojas, Virgilio E.; Soto-Becerra, Percy; Zeña-Ñañez, Sandra; Torres-Roman, J. Smith; Fernández-Mogollón, Jorge L.; Colchado-Palacios, Irina G.; Apolaya-Segura, Carlos E.; Dávila-Gonzales, Jhoni A.; Arce-Villalobos, Laura R.; Neciosup-Puican, Roxana del Pilar; Calvay-Requejo, Alexander G.; Maguiña, Jorge L.; Apolaya-Segura, Moisés; Díaz-Vélez, Cristian
“Objectives: To identify differences in the clinical and epidemiologic characteristics of patients during the first and second waves of the COVID-19 pandemic at the EsSalud Lambayeque health care network, Peru. Methods: An analytical cross-sectional study of 53,912 patients enrolled during the first and second waves of COVID-19 was conducted. Cluster analysis based on clustering large applications (CLARA) was applied to clinical-epidemiologic data presented at the time of care. The two pandemic waves were compared using clinical-epidemiologic data from epidemiologic surveillance. Results: Cluster analysis identified four COVID-19 groups with a characteristic pattern. Cluster 1 included the largest number of participants in both waves, and the participants were predominantly female. Cluster 2 included patients with gastrointestinal, respiratory, and systemic symptoms. Cluster 3 was the “severe” cluster, characterized by older adults and patients with dyspnea or comorbidities (cardiovascular, diabetes, obesity). Cluster 4 included asymptomatic, pregnant, and less severe patients. We found differences in all clinical-epidemiologic characteristics according to the cluster to which they belonged. Conclusion: Using cluster analysis, we identified characteristic patterns in each group. Respiratory, gastrointestinal, dyspnea, anosmia, and ageusia symptoms were higher in the second COVID-19 wave than the first COVID-19 wave“
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Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis
(Elsevier Ltd, 2022-07-18) Valladares-Garrido, Mario J.; Failoc-Rojas, Virgilio E.; Soto-Becerra, Percy; Zeña-Ñañez, Sandra; Torres-Roman, J. Smith; Fernández-Mogollón, Jorge L.; Colchado-Palacios, Irina G.; Apolaya-Segura, Carlos E.; Dávila-Gonzales, Jhoni A.; Arce-Villalobos, Laura R.; Neciosup-Puican, Roxana del Pilar; Calvay-Requejo, Alexander G.; Maguiña, Jorge L.; Apolaya-Segura, Moisés; Díaz-Vélez, Cristian
“Objectives: To identify differences in the clinical and epidemiologic characteristics of patients during the first and second waves of the COVID-19 pandemic at the EsSalud Lambayeque health care network, Peru. Methods: An analytical cross-sectional study of 53,912 patients enrolled during the first and second waves of COVID-19 was conducted. Cluster analysis based on clustering large applications (CLARA) was applied to clinical-epidemiologic data presented at the time of care. The two pandemic waves were compared using clinical-epidemiologic data from epidemiologic surveillance. Results: Cluster analysis identified four COVID-19 groups with a characteristic pattern. Cluster 1 included the largest number of participants in both waves, and the participants were predominantly female. Cluster 2 included patients with gastrointestinal, respiratory, and systemic symptoms. Cluster 3 was the “severe” cluster, characterized by older adults and patients with dyspnea or comorbidities (cardiovascular, diabetes, obesity). Cluster 4 included asymptomatic, pregnant, and less severe patients. We found differences in all clinical-epidemiologic characteristics according to the cluster to which they belonged. Conclusion: Using cluster analysis, we identified characteristic patterns in each group. Respiratory, gastrointestinal, dyspnea, anosmia, and ageusia symptoms were higher in the second COVID-19 wave than the first COVID-19 wave“
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COVID-19 Vaccine Effectiveness at a Referral Hospital in Northern Peru: A Retrospective Cohort Study
(MDPI, 2022-05-20) Valladares-Garrido, v; Zeña-Ñañez, Sandra; Peralta, C Ichiro; Puicón-Suárez, Jacqueline B; Díaz-Vélez, Cristian; Failoc-Rojas, Virgilio E
COVID-19 vaccines have achieved a significant reduction in mortality, yet objective estimates are needed in specific settings. We aimed to determine the effectiveness of COVID-19 vaccination at a referral hospital in Lambayeque, Peru. We conducted a retrospective cohort study from February to September 2021. We included hospitalized patients with COVID-19, whose data were stored in NotiWeb, a patient data system of the Peruvian Ministry of Health. We applied a propensity score-weighting method according to baseline characteristics of patients, and estimated hazard ratios (HR) using Cox regression models. Of 1553 participants, the average age was 55 years (SD: 16.8), 907 (58%) were male, and 592 (38%) deceased at 28-day follow-up. Before hospital admission, 74 (4.8%) had been immunized with at least one vaccine dose. Effectiveness against death in vaccinated patients was 50% at 90-day follow-up (weighted HR 0.50, 95% CI 0.28-0.89). Our results support the effectiveness of COVID-19 vaccination against death and provide information after early immunization in Peru.
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COVID-19 Vaccine Effectiveness at a Referral Hospital in Northern Peru: A Retrospective Cohort Study
(MDPI, 2022-05-20) Valladares-Garrido, v; Zeña-Ñañez, Sandra; Peralta, C Ichiro; Puicón-Suárez, Jacqueline B; Díaz-Vélez, Cristian; Failoc-Rojas, Virgilio E
COVID-19 vaccines have achieved a significant reduction in mortality, yet objective estimates are needed in specific settings. We aimed to determine the effectiveness of COVID-19 vaccination at a referral hospital in Lambayeque, Peru. We conducted a retrospective cohort study from February to September 2021. We included hospitalized patients with COVID-19, whose data were stored in NotiWeb, a patient data system of the Peruvian Ministry of Health. We applied a propensity score-weighting method according to baseline characteristics of patients, and estimated hazard ratios (HR) using Cox regression models. Of 1553 participants, the average age was 55 years (SD: 16.8), 907 (58%) were male, and 592 (38%) deceased at 28-day follow-up. Before hospital admission, 74 (4.8%) had been immunized with at least one vaccine dose. Effectiveness against death in vaccinated patients was 50% at 90-day follow-up (weighted HR 0.50, 95% CI 0.28-0.89). Our results support the effectiveness of COVID-19 vaccination against death and provide information after early immunization in Peru.
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Factors Associated with Knowledge of Evacuation Routes and Having an Emergency Backpack in Individuals Affected by a Major Earthquake in Piura, Peru
(MDPI, 2022-11-09) Valladares-Garrido, Mario J.; Zapata-Castro, Luis E.; Valdiviezo-Morales, Christopher G.; García-Vicente, Abigaíl; León-Figueroa, Darwin A.; Calle-Preciado, Raúl; Failoc-Rojas, Virgilio E.; Pereira-Victorio, César Johan; Díaz-Vélez, Cristian
Information on the prevention of earthquakes in Peru, a high-risk country, is still emerging. We determined the frequency and factors associated with knowledge of evacuation routes and the use of emergency backpacks in people affected by a major earthquake. A cross-sectional study using secondary data was conducted from August–December 2021 on people that experienced the 6.1 magnitude earthquake that occurred in Piura, Peru on 30 July 2021. The outcome was self-reported knowledge of evacuation routes and the use of emergency backpacks. The association with self-reported earthquake preparation training, use of sources of information on earthquakes, and sociodemographic variables was investigated. A total of 69.5% of participants knew evacuation routes, and 46.3% had an emergency backpack. A higher frequency of knowledge of evacuation routes was associated with previous training (PR: 1.47; 95% CI: 1.15–1.87), use of the media (PR: 1.35; 95% CI: 1.06–1.72), having received information from the COEN (PR: 1.19; 95% CI: 1.02–1.40), and with a greater number of household members (PR: 1.03; 95% CI: 1.01–1.06). There is a high frequency of knowledge of evacuation routes among participants. However, basic notions of prevention culture are still needed. This research contributes to policy development on earthquake preparation at the community level.
Acceso abierto
Factors Associated with Knowledge of Evacuation Routes and Having an Emergency Backpack in Individuals Affected by a Major Earthquake in Piura, Peru
(MDPI, 2022-11-09) Valladares-Garrido, Mario J.; Zapata-Castro, Luis E.; Valdiviezo-Morales, Christopher G.; García-Vicente, Abigaíl; León-Figueroa, Darwin A.; Calle-Preciado, Raúl; Failoc-Rojas, Virgilio E.; Pereira-Victorio, César Johan; Díaz-Vélez, Cristian
Information on the prevention of earthquakes in Peru, a high-risk country, is still emerging. We determined the frequency and factors associated with knowledge of evacuation routes and the use of emergency backpacks in people affected by a major earthquake. A cross-sectional study using secondary data was conducted from August–December 2021 on people that experienced the 6.1 magnitude earthquake that occurred in Piura, Peru on 30 July 2021. The outcome was self-reported knowledge of evacuation routes and the use of emergency backpacks. The association with self-reported earthquake preparation training, use of sources of information on earthquakes, and sociodemographic variables was investigated. A total of 69.5% of participants knew evacuation routes, and 46.3% had an emergency backpack. A higher frequency of knowledge of evacuation routes was associated with previous training (PR: 1.47; 95% CI: 1.15–1.87), use of the media (PR: 1.35; 95% CI: 1.06–1.72), having received information from the COEN (PR: 1.19; 95% CI: 1.02–1.40), and with a greater number of household members (PR: 1.03; 95% CI: 1.01–1.06). There is a high frequency of knowledge of evacuation routes among participants. However, basic notions of prevention culture are still needed. This research contributes to policy development on earthquake preparation at the community level.
Acceso abierto
Factors Associated with Knowledge of Evacuation Routes and Having an Emergency Backpack in Individuals Affected by a Major Earthquake in Piura, Peru
(MDPI, 2022-11-09) Valladares-Garrido, Mario J.; Zapata-Castro, Luis E.; Valdiviezo-Morales, Christopher G.; García-Vicente, Abigaíl; León-Figueroa, Darwin A.; Calle-Preciado, Raúl; Failoc-Rojas, Virgilio E.; Pereira-Victorio, César Johan; Díaz-Vélez, Cristian
Information on the prevention of earthquakes in Peru, a high-risk country, is still emerging. We determined the frequency and factors associated with knowledge of evacuation routes and the use of emergency backpacks in people affected by a major earthquake. A cross-sectional study using secondary data was conducted from August–December 2021 on people that experienced the 6.1 magnitude earthquake that occurred in Piura, Peru on 30 July 2021. The outcome was self-reported knowledge of evacuation routes and the use of emergency backpacks. The association with self-reported earthquake preparation training, use of sources of information on earthquakes, and sociodemographic variables was investigated. A total of 69.5% of participants knew evacuation routes, and 46.3% had an emergency backpack. A higher frequency of knowledge of evacuation routes was associated with previous training (PR: 1.47; 95% CI: 1.15–1.87), use of the media (PR: 1.35; 95% CI: 1.06–1.72), having received information from the COEN (PR: 1.19; 95% CI: 1.02–1.40), and with a greater number of household members (PR: 1.03; 95% CI: 1.01–1.06). There is a high frequency of knowledge of evacuation routes among participants. However, basic notions of prevention culture are still needed. This research contributes to policy development on earthquake preparation at the community level.
Acceso abierto
Mental Disorders and Level of Resilience in Eight High-Altitude Cities of Peru during the Second Pandemic Wave: A Multicenter Population-Based Study
(MDPI, 2022-12-28) Zila-Velasque, J. Pierre; Grados-Espinoza, Pamela; Coba-Villan, Naomi; Quispe-Chamorro, Jocelyn; Taipe-Guillén, Yesenia F.; Pacheco, Estefany; Ccasa-Valero, Laura; Failoc-Rojas, Virgilio E.; Díaz-Vélez, Cristian; Valladares-Garrido, Mario J.
COVID-19 has led us to take preventive measures, such as social isolation, to reduce the high transmissibility of the disease. This could have affected the mental health of various population groups and the development of resilience as a mitigator. A cross-sectional analytical study was conducted with 700 participants from eight cities. The dependent variables were depression, anxiety, and post-traumatic stress disorder (PTSD). The independent variable was resilience. Generalized logistic regressions were used to identify the associations between the variables. The population consisted mostly of university students (65.0%); the rest of the population was distributed among workers of public or private institutions, housewives, and others (35.0%). High prevalences of anxiety (72.7%), depression (64.1%), and PTSD (15.1%) were found, as well as a median (interquartile range) resilience score of 24 points was determined. Factors associated with a high prevalence of PTSD were having lost employment and having a family member who died from COVID-19. For depression, associated factors were severe food insecurity and hypersomnia. For anxiety, associated factors were were having a deceased family member with COVID-19 and mild food insecurity. Our results show that, during the pandemic, the general population had a higher prevalence of mental disorders. In addition, anxiety was the most prevalent of the dependent variables. Special attention should be paid to the factors influencing the development of mental disorders and mental health prevention and promotion programs should be established.
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Mental Health Disturbance after a Major Earthquake in Northern Peru: A Preliminary, Cross-Sectional Study
(MDPI, 2022-07-08) Valladares-Garrido, Mario J.; Zapata-Castro, Luis E.; Domínguez-Troncos, Helena; García-Vicente, Abigaíl; León-Figueroa, Darwin A.; Zila-Velasque, J. Pierre; Grados-Espinoza, Pamela; Astudillo-Rueda, David; Peralta, C. Ichiro; Díaz-Vélez, Cristian
Little has been studied in Peru on the mental health repercussions after a major earthquake.We aimed to explore the factors associated with depressive and anxiety symptoms in people whoexperienced a 6.1 magnitude earthquake in Piura, Peru, on 30 July 2021. A preliminary cross-sectional study was conducted in the general population between August–September 2021. An onlinequestionnaire was provided using PHQ-9, GAD-7, and other relevant measures. Generalized linearmodels were applied. Of the 177 participants, the median age was 22 years, the majority were female(56%), and many experienced depressive (52%) or anxiety symptoms (52%). Presence of depressivesymptoms was associated with a personal history of mental disorder, moderate housing damage,social/material support from politicians, moderate food insecurity, and insomnia. Presence of anxietysymptoms was associated with physical injury caused by the earthquake, mild food insecurity, andinsomnia. The development of depressive and anxiety symptoms following the 2021 earthquakeexperienced in Piura depended on multiple individual and socioeconomic factors. Additional studiesshould reinforce the factors identified here given the methodological limitations, such as the studydesign, sampling method, and sample size. This would lead to effective intervention measures tomitigate the impact of earthquakes on mental health.
Acceso abierto
Mental Health Disturbance after a Major Earthquake in Northern Peru: A Preliminary, Cross-Sectional Study
(MDPI, 2022-07-08) Valladares-Garrido, Mario J.; Zapata-Castro, Luis E.; Domínguez-Troncos, Helena; García-Vicente, Abigaíl; León-Figueroa, Darwin A.; Zila-Velasque, J. Pierre; Grados-Espinoza, Pamela; Astudillo-Rueda, David; Peralta, C. Ichiro; Díaz-Vélez, Cristian
Little has been studied in Peru on the mental health repercussions after a major earthquake.We aimed to explore the factors associated with depressive and anxiety symptoms in people whoexperienced a 6.1 magnitude earthquake in Piura, Peru, on 30 July 2021. A preliminary cross-sectional study was conducted in the general population between August–September 2021. An onlinequestionnaire was provided using PHQ-9, GAD-7, and other relevant measures. Generalized linearmodels were applied. Of the 177 participants, the median age was 22 years, the majority were female(56%), and many experienced depressive (52%) or anxiety symptoms (52%). Presence of depressivesymptoms was associated with a personal history of mental disorder, moderate housing damage,social/material support from politicians, moderate food insecurity, and insomnia. Presence of anxietysymptoms was associated with physical injury caused by the earthquake, mild food insecurity, andinsomnia. The development of depressive and anxiety symptoms following the 2021 earthquakeexperienced in Piura depended on multiple individual and socioeconomic factors. Additional studiesshould reinforce the factors identified here given the methodological limitations, such as the studydesign, sampling method, and sample size. This would lead to effective intervention measures tomitigate the impact of earthquakes on mental health.
Acceso abierto
Post-Traumatic Stress Disorder after the 6.1 Magnitude Earthquake in Piura, Peru: A Cross-Sectional Study
(MDPI, 2022-09-03) Valladares-Garrido, Mario J.; Zapata-Castro, Luis E.; Peralta, C. Ichiro; García-Vicente, Abigaíl; Astudillo-Rueda, David; León-Figueroa, Darwin A.; Díaz-Vélez, Cristian
“: In Peru, major disasters like the 2007 Pisco earthquake have produced high rates of posttraumatic stress. However, evidence is still needed to strengthen interventions. In 2021, a major earthquake struck Piura, in northern Peru. In this context, we aimed to assess the prevalence of PTSD and its associated factors. A cross-sectional study was conducted during August–September 2021 in people who experienced the 6.1 Piura earthquake on 30 July 2021. The questionnaire included the PCL-C, CD-RISC, ISI, HFIAS, and additional demographic data. Generalized linear models were used. The prevalence of PTSD was 20.3%. Household income was between PEN 2001 and 3000 (PR = 4.26, 95% CI: 1.08–16.75), smoking (PR = 2.49, 95% CI: 1.03–6.01), experience of a nervous breakdown (PR = 1.83, 95% CI: 1.09–3.09), moderate food insecurity (PR = 2.91, 95% CI: 1.10–7.73), and severe insomnia (PR = 8.25, 95% CI: 2.22–30.71) increased the prevalence of PTSD. One out of five individuals experienced post-traumatic stress symptoms after the 2021 earthquake in Piura, which varies depending on socioeconomic, psychosocial, and individual factors. Further research should strengthen these findings to ensure a fair and early mental health intervention against new seismic events in this and other Peruvian regions.“
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Prevalence and Factors Associated with Anxiety and Depression in Peruvian Medical Students
(MDPI, 2022-02-07) Piscoya-Tenorio, Jorge L.; Heredia-Rioja, Walter V.; Morocho-Alburqueque, Noelia; Zeña-Ñañez, Sandra; Hernández-Yépez, Palmer J.; Díaz-Vélez, Cristian; Failoc-Rojas, Virgilo E.; Valladares-Garrido, Mario J.
“: During medical training, students are exposed to stressors that deteriorate mental health. This study determined depression and anxiety prevalence and their associated factors in students from four medical schools in northern Peru. A cross-sectional study was conducted among medical students from Lambayeque, Peru. The Goldberg Anxiety and Zung Depression tests were applied. The dependent variables were depression and anxiety, and their association with covariates (age, sex, type of university, socioeconomic level, experience, family problem, and physical activity) was evaluated. Prevalence ratios were calculated using generalized linear models. Of 482 students, the prevalence of anxiety was 61.8% and depression was 22.0%. A severe level of anxiety was observed in 6.2% in the group between 16 and 20 years old. It was observed that private university students had higher frequencies of having depression (PR = 2.01) and anxiety (PR = 1.35); males had a lower risk of anxiety (PR = 0.82), but higher risk of depression compared to females (PR = 1.45). Performing physical activity decreased the prevalence of depression (PR = 0.53); however, it increased the frequency of anxiety (PR = 1.26). Having family problems increased the prevalence of anxiety (PR = 1.26). Medical students from private universities experienced higher rates of depression and anxiety. Depression and anxiety were associated with gender and physical activity. These findings highlight the importance of mental health promotion due to its link with quality of life and academic performance.“
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Smartphone overuse, depression & anxiety in medical students during the COVID-19 pandemic
(Public Library of Science, 2022-08-30) Santander-Hernández, Flor M.; Peralta, C. Ichiro; Guevara-Morales, Miguel A.; Díaz-Vélez, Cristian; Valladares-Garrido, Mario J.
“Introduction Medical students have made particular use of smartphones during the COVID-19 pandemic. Although higher smartphone overuse has been observed, its effect on mental disorders is unclear. This study aimed to assess the association between smartphone overuse and mental disorders in Peruvian medical students during the COVID-19 pandemic. Methods A cross-sectional study was conducted in 370 students aged between 16 and 41 years (median age: 20) in three universities from July to October 2020. A survey including Smartphone Dependence and Addiction Scale, PHQ-9, and GAD-7 was applied. Prevalence ratios were estimated using generalized linear models. Results Smartphone overuse was a common feature among students (n = 291, 79%). Depressive symptoms were present in 290 (78%) students and anxiety symptoms in 255 (69%). Adjusted for confounders, addictive/dependent smartphone use was significantly associated with presence of depressive symptoms (PR = 1.29, 95% CI: 1.20–1.38 for dependent use; PR = 1.30, 95% CI: 1.12–1.50 for addictive use). Also, addictive/dependent smartphone use was significantly associated with presence of anxiety symptoms (PR = 1.59, 95% CI: 1.14–2.23 for dependent use; PR = 1.61, 95% CI: 1.07–2.41 for addictive use). Conclusions Our findings suggest that medical students exposed to smartphone overuse are vulnerable to mental disorders. Overuse may reflect an inappropriate way of finding emotional relief, which may significantly affect quality of life and academic performance. Findings would assist faculties to establish effective measures for prevention of smartphone overuse. “