Examinando por Autor "Delgado Cubas, Luz Mery"

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Acceso abierto
Efecto antibacteriano del extracto etanólico del cáliz de Physalis peruviana (Aguaymanto) frente cepas de referencia, Lima Metropolitana, 2023
(Universidad Privada Norbert Wiener, 2024-05-04) Delgado Cubas, Luz Mery; Trujillo Paredes, Edith; Collanque Pinto, Jesús Daniel
Antibiotic resistance is a major global concern, with Streptococcus mutans, Porphyromonas gingivalis, and Staphylococcus aureus among the main pathogens involved. In this context, the objective of the present study was to determine the antibacterial effect of the ethanolic extract of Physalis peruviana (cape gooseberry) calyx against reference strains in Lima, 2023. The research followed a hypothetical-deductive method with a quantitative approach, classified as applied research, using an experimental cross-sectional explanatory-level design. The study population consisted of Physalis peruviana fruits and the bacterial strains Streptococcus mutans, Porphyromonas gingivalis, and Staphylococcus aureus. The sample included 10 kilograms of Physalis peruviana calyx and 15 Petri dishes, distributed into five plates per strain, with intentional non-probabilistic sampling. The phytochemical procedure consisted of a preliminary qualitative analysis, and the biological assay was performed using agar well diffusion. Results showed that the mean inhibition zones at concentrations of 25%, 50%, and 75% were lower than those observed for the positive controls (chlorhexidine and ciprofloxacin). Moreover, statistically significant differences were found between the experimental groups and the DMSO control (p<0.000). In conclusion, the ethanolic extract of Physalis peruviana calyx exhibited antibacterial activity at all tested concentrations against the reference strains in Lima, 2023, except at the 25% concentration, which showed a mean inhibition zone of 7.2160 mm against Streptococcus mutans ATCC 25175.