Examinando por Autor "Escarza Aquino, Katherine Hortensia"

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    Interacciones medicamentosas potenciales en prescripciones médicas de pacientes ambulatorios del servicio de psiquiatría del Hospital III de Emergencias Grau EsSalud, periodo abril–noviembre del 2017
    (Universidad Privada Norbert Wiener, 2021-06-22) Escarza Aquino, Katherine Hortensia; Salas Milla, Karina; Torres Veliz, Ernesto Raúl
    Our study, "Potential Drug-Drug Interactions Frequently Present in the Psychiatry Service of the Hospital III de Emergencias Grau EsSalud, April – November 2017," had the Objective of determining the Potential Drug-Drug Interactions (PDDIs) present in medical prescriptions for outpatient psychiatry patients. Methodology: The study was retrospective, descriptive, and cross-sectional. A total of 632 medical prescriptions were analyzed. Results: 1,296 potential drug interactions were found. The most frequent PDDIs were: clonazepam–sertraline (8.7%), clonazepam–fluoxetine (4.0%), and biperiden–risperidone (3.9%). By mechanism, pharmacokinetic accounted for 30% and pharmacodynamic for 70%. By degree of severity, minor severity was 4.4%, moderate severity was 87.1%, and major severity was 8.5%. The most frequently implicated drugs in the PDDIs were: clonazepam (17.6%), sertraline (13.5%), and biperiden (8.6%). The most frequent diagnoses found were: mixed anxiety and depressive disorder (25.9%), paranoid schizophrenia (14.2%), and moderate depressive episode (11.4%). Conclusion: 66% of the population presented at least one potential drug interaction, and 34% presented no type of interaction in the psychiatry service of the Hospital III de Emergencias Grau-EsSalud.