Examinando por Autor "Espinoza Canales, Carolina Desidet De Jesús"

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    Comparative effectiveness of trisodium citrate and heparin for extracorporeal circuit anticoagulation in adults with renal failure undergoing renal replacement therapy.
    (Universidad Privada Norbert Wiener, 2018-11-04) Espinoza Canales, Carolina Desidet De Jesús; Pretell Aguilar, Rosa Maria
    Objective: To analyze and systematize the evidence on the effectiveness of trisodium citrate versus heparin for anticoagulation of the extracorporeal system in adult patients with renal failure undergoing renal replacement therapy. Materials and methods: A systematic review of eleven scientific articles with a maximum age of ten years. According to the type of research, 54.5% are systematic reviews, 18.2% are clinical trials, 18.2% are retrospective cohorts, and 9.1% are meta-analyses. Regarding quality, 81.8% are of high quality and 18.2% are of moderate quality. 36.4% of the evidence comes from China, followed by 36.4% from England, 9.1% from Switzerland, 9.1% from Austria, and 9.0% from Amsterdam. A summary table was prepared with the main data from each selected article. Results: 100% of the evidence indicates that the use of trisodium citrate is more effective for anticoagulation of the extracorporeal circuit in adult patients with renal failure undergoing renal replacement therapy, in terms of filter lifespan, lower bleeding risk, and less circuit loss. Conclusions: The use of citrate is more effective compared to heparin in adult patients undergoing renal replacement therapy for anticoagulation of the extracorporeal circuit.