Examinando por Autor "Flores Chipana, Ciprian"

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Acceso abierto
Effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients
(Universidad Privada Norbert Wiener, 2017-12-03) Félix Saavedra, Flor de María; Flores Chipana, Ciprian; Pretell Aguilar, Rosa Maria
Objective: To systematize the evidence on the effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients. Methodology: An observational and retrospective systematic review, where the search was restricted to full-text articles, and the selected articles underwent critical reading using the GRADE evaluation system to determine their level of evidence. In the final selection, 10 articles were chosen, of which 60% were meta-analyses and 20% were systematic reviews with high evidence quality and strong recommendation strength. Of these, 30% (3) were from China, 10% (1) from Austria, 10% (1) from the United States, and 10% (1) from India. Regarding systematic reviews, 10% (1) were from the USA and 10% (1) from China. With 20% being clinical trials and cohort studies with moderate evidence quality and weak recommendation strength, 10% (1) were from Portugal and 10% (1) from the United States. Results: Among the reviewed evidence, 70% affirm that therapeutic hypothermia contributes to neuroprotection in post-cardiac arrest patients, while 30% suggest that therapeutic hypothermia does not provide any benefit in neurocritical post-cardiac arrest patients. Conclusions: The best-reviewed evidence demonstrates that therapeutic hypothermia reduces neurological damage after cardiac arrest in neurocritical patients.
Acceso abierto
Effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients
(Universidad Privada Norbert Wiener, 2017-12-03) Félix Saavedra, Flor de María; Flores Chipana, Ciprian; Pretell Aguilar, Rosa Maria
Objective: To systematize the evidence on the effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients. Methodology: An observational and retrospective systematic review, where the search was restricted to full-text articles, and the selected articles underwent critical reading using the GRADE evaluation system to determine their level of evidence. In the final selection, 10 articles were chosen, of which 60% were meta-analyses and 20% were systematic reviews with high evidence quality and strong recommendation strength. Of these, 30% (3) were from China, 10% (1) from Austria, 10% (1) from the United States, and 10% (1) from India. Regarding systematic reviews, 10% (1) were from the USA and 10% (1) from China. With 20% being clinical trials and cohort studies with moderate evidence quality and weak recommendation strength, 10% (1) were from Portugal and 10% (1) from the United States. Results: Among the reviewed evidence, 70% affirm that therapeutic hypothermia contributes to neuroprotection in post-cardiac arrest patients, while 30% suggest that therapeutic hypothermia does not provide any benefit in neurocritical post-cardiac arrest patients. Conclusions: The best-reviewed evidence demonstrates that therapeutic hypothermia reduces neurological damage after cardiac arrest in neurocritical patients.