Examinando por Autor "Huayta Pillco, Fiorela"

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    Interacciones medicamentosas potenciales asociados a polifarmacia en prescripciones de pacientes de la Unidad de Cuidados Intensivos de la Clínica San Pablo, febrero–abril 2021
    (Universidad Privada Norbert Wiener, 2021-10-04) Huayta Pillco, Fiorela; Torres Veliz, Ernesto Raúl
    This research aimed to determine the relationship between polypharmacy and the presence of potential drug interactions by evaluating prescriptions for patients in the Intensive Care Unit of a local clinic. A descriptive, prospective, and correlational study was conducted, using a data collection form as the instrument. The Micromedex database was used to evaluate pharmacotherapy, and the Pearson's Chi-squared test and Spearman's Rho Correlation Coefficient were used for hypothesis testing. A total of 283 prescriptions were evaluated, with 51.9% containing 6 to 10 medications. The most common comorbidity was arterial hypertension (46.3%), and 57.6% of the patients were aged between 50 and 69. Regarding interaction frequency, 46.6% of prescriptions had 1 to 5 interactions, followed by 35.4% with 6 to 10 interactions. The most frequent therapeutic group involved was opioid analgesics (22.6%). The most predominant type of interaction was pharmacodynamic (66%), and 61.8% had a major severity level. Finally, it was determined that polypharmacy is significantly related to the presence of potential drug interactions.