Examinando por Autor "Justil Guerrero, Hugo Jesús"

Mostrando 1 - 20 de 38

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Actividad antidepresiva del extracto etanólico de las hojas de Manihot esculenta Cranz “yuca” en ratones
(Universidad Privada Norbert Wiener, 2023-02-20) Gallardo Delgado, Shirley Jasmin; Justil Guerrero, Hugo Jesús
Depression is a mood disorder characterized by feelings of sadness, with episodes lasting weeks or months, often leading to suicidal thoughts. According to the "WHO," this disease is very common worldwide, affecting more than 280 million people. Over half of those affected do not receive treatment due to a lack of resources or misdiagnosis. Objective: The present study aimed to evaluate the antidepressant activity of the ethanolic extract of Manihot esculenta Cranz leaves ("cassava") in mice. Methodology: The study was experimental and quantitative. The leaves were collected in the district of La Merced, Province of Chanchamayo, Department of Junín. Secondary metabolites of the ethanolic extract were identified. The antidepressant activity (AAD) was evaluated using the forced swimming test in 30 albino mice at doses of 50, 100, and 200 mg/kg of the ethanolic extract administered orally, compared to fluoxetine at 20 mg/kg. Immobility time, swimming time, and climbing time were measured over 15 minutes. Results: The lowest average immobility time was observed in the group treated with the ethanolic extract at 200 mg/kg, with 13.5 seconds, while the control group showed a significantly higher immobility time of 104.2 seconds. The swimming time was highest in the group treated with 200 mg/kg of the ethanolic extract, averaging 177.5 seconds, as was the climbing time, averaging 49.0 seconds. Conclusion: The ethanolic extract at a concentration of 200 mg/kg has antidepressant activity comparable to fluoxetine.
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Actividad antioxidante y antimicrobiana de Schkuhria pinnata "Canchalagua" en estudios in vitro: una revisión sistemática
(Universidad Privada Norbert Wiener, 2021-07-06) Huamán Segura, Kattia Vanessa; Meza Carhuamaca, Ana Elizabeth; Justil Guerrero, Hugo Jesús
The plant species Schkuhria Pinnata, 'Canchalagua,' is traditionally used for its antioxidant and antimicrobial activities. The objective was to evaluate the efficacy of the antimicrobial and antioxidant activity of Schkuhria Pinnata, 'Canchalagua,' in inhibiting bacterial growth and reducing free radicals. A systematic intervention review study was conducted. Eligibility criteria were initially established, followed by a search in the Renati, Alicia (Concytec), Scielo, PubMed, Elsevier, Lilacs, Virtual Health Library (VHL), and Google Scholar databases. Studies were selected using the PRISMA method. A total of 103 articles were obtained, from which 11 studies were selected for data extraction and bias assessment, described by the Joanna Briggs Institute (2014). Metabolites were identified and quantified in different parts of the plant using precipitation, coloration, foaming, Folin-Ciocalteu, and aluminum chloride colorimetric methods. For the evaluation of antioxidant activity, the DPPH and ABTS methods were used, and the extracts showed reduction of free radicals. For antimicrobial activity, agar diffusion and dilution methods were employed. The extracts presented inhibition against Propionibacterium acnes, Pseudomonas aeruginosa, Escherichia coli, Enterococcus faecalis, Staphylococcus aureus, Mycobacterium smegmatis, Malephora lutea, and Staphylococcus epidermidis. Metabolites responsible for the antioxidant and antimicrobial activity were identified, and Schkuhria Pinnata, 'Canchalagua,' demonstrated efficacy in reducing free radicals and inhibiting bacteria.
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Automedicación con AINEs en usuarios con patologías osteomusculares que acuden a boticas Inkafarma Villasol – Los Olivos – Lima Metropolitana, 2021–2022
(Universidad Privada Norbert Wiener, 2022-10-05) Consuelo Cruz, Haydee Isandra; Orihuela Juica, Mery Aracelly; Justil Guerrero, Hugo Jesús
The objective of this research was to "Determine the relationship between self-medication with NSAIDs and musculoskeletal pathologies among users visiting Inkafarma Villasol Drugstores in Los Olivos, Metropolitan Lima, 2021–2022." Method: This was a hypothetical-deductive study, a basic type, with a quantitative approach. The sample consisted of 385 users. The instrument was a survey validated by subject matter experts. Data collection and processing were performed using the SPSS Version 25.0 statistical program and the Pearson's Chi-squared test. Result: The analysis of the relationship between self-medication with NSAIDs and musculoskeletal pathologies found a significant relationship (p value=0.000). For the relationship between anti-inflammatory preference and musculoskeletal pathologies, a significant relationship was found for diclofenac (p value=0.009), naproxen (p value=0.021), and meloxicam (p value=0.001). Conclusion: A significant relationship was determined to exist between self-medication with NSAIDs and musculoskeletal pathologies, with 50% self-medicating for an intermediate period until they achieved improvement.
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Automedicación y efecto adverso de antibioticos en pacientes de la botica Jan del distrito de San Juan de Miraflores 2021
(Universidad Privada Norbert Wiener, 2022-05-20) Esquivel Chauca, Carlos Alberto; Justil Guerrero, Hugo Jesús
The study used a quantitative, basic, correlational, non-experimental, cross-sectional approach. The technique was observation, and the instrument was a survey applied to 168 users. Data were analyzed with descriptive statistics presented in tables and figures. The results indicate the relationship between self-medication and adverse effects at the Jan drugstore in the San Juan de Miraflores district in 2021. For 'associated disease,' 58.9% expressed that chills almost never led them to self-medication. For 'knowledge of the consequence of self-medication,' 96.2% indicated they knew about the action and use of antimicrobials. For 'prevalence,' 38.1% reported that they never recommend self-medication to others. For 'pharmacological group,' 69.6% indicated that amphenicols always caused them some adverse effect. For 'affected systems,' 39.9% indicated that the adverse effect almost always affects their gastrointestinal system. For 'type of symptoms,' 39.3% stated that they almost always suffer from vomiting. It is concluded that the relationship between self-medication and adverse effects with antibiotics in patients of the Jan drugstore in the San Juan de Miraflores district in 2021 was highly significant and moderate positive (r=0.665;p=0.000<0.05).
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Calidad de servicio y adherencia terapéutica en pacientes con enfermedad crónica atendidos en la botica Ariasfarma en el distrito de San Miguel, Lima – marzo 2021
(Universidad Privada Norbert Wiener, 2022-11-30) Armijo Abrego, Wilmer Alfredo; Justil Guerrero, Hugo Jesús
The objective of this research was to evaluate the relationship between service quality and therapeutic adherence in patients with chronic diseases who were served at the Ariasfarma drugstore in the San Miguel district, Lima, in March 2021. Methodology: A correlational, cross-sectional-prospective design was used. The sample consisted of 120 patients with chronic diseases (arterial hypertension, diabetes mellitus, and dyslipidemias). Results: Spearman's Rho determined that the p-value was 0.455 (p > 0.05), meaning there is no relationship between the study variables. It was also observed that the majority of patients with chronic diseases were female (59.2%) and in the 54-71 age range (51.7%), with arterial hypertension (41.7%) being the most prevalent disease. Patients rated the service quality as very good (35.8%), good (63.3%), and fair (0.8%). The level of therapeutic adherence was high (60%) and medium (40%). Conclusion: It is concluded that no relationship exists between service quality and therapeutic adherence in patients with chronic diseases who were served at the Ariasfarma drugstore in the San Miguel district, Lima, in March 2021.
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Cumplimiento de buenas prácticas de prescripción en recetas médicas atendidas en botica Mi Perú, Los Olivos 2022
(Universidad Privada Norbert Wiener, 2023-07-21) Guevara Santacruz, Gladys; Uriarte Chuquilín, Adelmo; Justil Guerrero, Hugo Jesús
The present research was titled Compliance with Good Prescription Practices in Medical Prescriptions Attended at Mi Perú Pharmacy, Los Olivos 2022. The objective was to evaluate the overall compliance with good prescription practices in standard medical prescriptions attended at Mi Perú Pharmacy, Los Olivos 2022. The method used was deductive, with a quantitative approach, basic in nature, and a non-experimental design. This study included a population of 607 users, from which a non-probabilistic sample of 305 users was studied, applying the observation technique through a checklist comprising 17 indicators: 06 for prescriber data, 07 for medication data, and 04 for patient data. When evaluating the overall compliance with good prescription practices, it was found that the indicators were met. Similarly, for the dimensions of prescriber data, medication data, and patient data, the indicators were also met. The conclusion reached is that there is 100% compliance with good prescription practices in medical prescriptions attended at Mi Perú Pharmacy, Los Olivos 2022.
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Cumplimiento de las buenas prácticas de prescripción de recetas atendidas en la farmacia del consultorio externo del Hospital Nacional Dos de Mayo Cercado de Lima: agosto-diciembre, 2018
(Universidad Privada Norbert Wiener, 2019-10-11) Espinoza Flores, Moner Felix; Justil Guerrero, Hugo Jesús
Regarding the prescriber's data, it was observed that they comply with the 2 indicators: prescriber's signature and seal 100%, issue date 99.6%, and do not comply and 2 indicators: expiration date 98.7%, Information to the Pharmacist, 99.5%. Likewise, regarding the medication data, it was observed that they comply with the 9 indicators, international non-proprietary name 99.2%. National request for essential single medications, 88.6%, prescription for medication by correct concentration 98.3%, pharmaceutical form 98.2%, total prescribed amount 99%, prescription with medication with Dose 94.2%, route of administration 84.4%, Dose frequency 92.9%, duration of treatment 75.7%, Conclusions. It was determined that most of the indicators comply, while a minority of the indicators do not, according to the good prescribing practices standard for standardized single prescriptions, served in the outpatient clinic pharmacy.
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Diversidad de medicamentos usados en terapia COVID-19, en usuarios de boticas el Milagro. Distrito de Ventanilla – Provincia Callao. 2021–2022
(Universidad Privada Norbert Wiener, 2022-10-04) Mendoza López, Edgardo; Justil Guerrero, Hugo Jesús
Objective: To describe the diversity of medications most used for COVID-19 therapy among users visiting "El Milagro" drugstores. Method: This study used a quantitative approach, a basic type, a non-experimental design, and a descriptive level. A sample of 114 users was taken, and a survey was used as the data collection technique. Statistical analysis was performed using descriptive statistics with the contingency or cross-tabulation table for the respective variables. Results: The young adult age group (18-26 years) was the most frequent among users visiting the drugstores as well as regarding the diversity of medications most used for COVID-19 therapy. Regarding the diversity of most used medications, 28.1% of users presented signs and symptoms, 59.6% presented signs and symptoms of a certain intensity, 44.7% were young adults, and 53.5% were male.
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Efecto antiinflamatorio y capacidad antioxidante del extracto hidroalcohólico del pericarpio de Nephelium lappaceum L. "rambután"
(Universidad Privada Norbert Wiener, 2020-01-30) Salazar Barrios, Evelin Patricia; Palomino Ludeña, Mirian; Justil Guerrero, Hugo Jesús
The objective was to determine the anti-inflammatory effect and antioxidant capacity of the hydroalcoholic extract from the pericarp of Nephelium lappaceum L. 'rambutan.' Method: For the anti-inflammatory effect, the 3% carrageenan-induced plantar edema model (Winter et al. modified) was used. Seven groups of six mice were formed. After one hour, 0.1 mL of 3% carrageenan was administered, and the edema of the inflamed paw was measured at 1, 2, 3, and 4 hours. For the antioxidant capacity, the modified Lalitha and Selvam method was used. 6 mL of blood was extracted, and eight groups of three replicates each were prepared. The samples were centrifuged at 1500 rpm for 10 minutes, and the absorbance was measured at 415 nm at 50 and 90 minutes. Results: The 500 mg/kg dose showed the highest anti-inflammatory effect (22.58%) at the 4-hour mark. For antioxidant capacity, the 50 µg/mL concentration yielded the best result at 50 minutes (95.54%), while the 100 µg/mL concentration was the best at 90 minutes (77.95%). Conclusion: The anti-inflammatory effect and antioxidant capacity of the hydroalcoholic extract from the pericarp of Nephelium lappaceum L. 'rambutan' were confirmed.
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Efectos adversos atribuidos a la vacuna contra el coronavirus (COVID-19) en participantes que acuden al vacunatón en el distrito de San Juan de Miraflores. Lima 2021
(Universidad Privada Norbert Wiener, 2022-07-08) Bautista Santa Cruz, Josselyn Yanet; Chipana Blas, Judith Pamela; Justil Guerrero, Hugo Jesús
COVID-19 has caused many deaths in Peru and worldwide. Since its appearance, the only way to combat it and prevent the severity of its symptoms has been through vaccination. The objective of this research was to analyze the adverse effects attributed to the coronavirus (COVID-19) vaccine in participants attending a vaccination event in the San Juan de Miraflores district. The study was deductive, with a quantitative approach, an applied type, and a non-experimental, observational, and cross-sectional design. The sample was 384 participants selected by systematic probabilistic sampling. The technique was a survey, the instrument was a questionnaire, and the processing of tables and figures was performed using Excel and SPSS statistical software. Results: The most frequent adverse effects at the injection site were pain (83.9%), inflammation (6.3%), and redness (5.7%). The most frequent somatic adverse effects were general malaise (89.3%), muscle pain (64.6%), and fever (24.7%). The intensity of the adverse effects at both the injection site and the somatic level was mild. Women reported more local adverse effects, while men reported more somatic effects. In conclusion, the COVID-19 vaccine administered to residents of the San Juan de Miraflores district at the Vaccinathon presents mild adverse effects, and it is suggested that vaccination continue to protect and immunize the greatest number of residents.
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Efectos adversos de la inmunización contra el COVID-19 en pobladores que acudieron a vacunarse en el distrito de Villa El Salvador de Lima Metropolitana, 2021–2022
(Universidad Privada Norbert Wiener, 2022-07-07) Vila Alvarez, Daniel; Saldivar Anticona, Leonora Vanessa; Justil Guerrero, Hugo Jesús
The objective was to determine the adverse effects of COVID-19 immunization among residents who went to get vaccinated in the district of Villa el Salvador, Metropolitan Lima, from 2021 to 2022. Method: The study used a quantitative approach with a basic type, a non-experimental design, and an observational, cross-sectional descriptive level. A questionnaire was applied to a sample of 385 people, and the technique was a survey. Result: Of the 385 participants, local reactions reported were: pain (71.2% or 274), numbness (18.7% or 72), inflammation (15.1% or 58), and redness (7.0% or 27). Systemic adverse reactions included muscle pain (37.9% or 146), general malaise (29.4% or 113), headache (28.8% or 111), fatigue (23.1% or 89), fever (15.8% or 61), and chills (13.8% or 53). Conclusion: Both local and systemic adverse reactions were of mild to moderate intensity. There were reports of severe incidence that required medical attention but were resolved within a few days. Young people and adults had a higher incidence of adverse reactions. Women also reported a higher frequency of adverse reactions than men. Additionally, people with nutritional deficiencies, metabolic diseases, and eating disorders tend to have an increased rate of local and systemic adverse reactions.
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Errores de prescripción de recetas atendidas en una oficina farmacéutica de Inkafarma San Juan 1. Lima 2021
(Universidad Privada Norbert Wiener, 2021-08-04) Callampi Vilca, Henry Anival; Justil Guerrero, Hugo Jesús
The irrational use of medicines is a global problem due to medication errors, with prescribing being the most common error. The objective of this research was to evaluate prescribing errors in prescriptions filled at an Inkafarma pharmaceutical office in San Juan 1, Lima, in 2021. Methodology: The study was applied type, with a deductive method, and an observational, prospective, cross-sectional design. The population consisted of 2,000 prescriptions, of which 322 were analyzed. A data collection form was used as the instrument, covering four dimensions: prescriber data, patient data, medication data, and prescription legibility, all of which must comply with the manual of good prescribing practices. Results: In the patient data dimension, 61.8% were non-compliant. In the medication data dimension, 69.3% were non-compliant. In the prescriber data dimension, there was a minimum error of 0.9%, and for legibility, 7.1% were non-compliant. Conclusion: All of the analyzed prescriptions presented at least one error in their dimensions. Patient data had the highest overall error rate, with the INN (International Nonproprietary Name) indicator specifically having 20.5% of errors.
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Errores de prescripción en las recetas atendidas en la farmacia ambulatoria del Centro Médico Naval en el periodo enero a marzo del 2021. Lima 2021
(Universidad Privada Norbert Wiener, 2021-08-02) Rodriguez Escobar, Vanesa; Justil Guerrero, Hugo Jesús
Medication errors account for approximately 16%, equivalent to 80,000 deaths per year. This problem is linked to multiple factors that converge to produce a severely negative impact on both the patient and the healthcare system. The present research aims to provide information on prescription errors so that healthcare facilities can implement protocols to help reduce the error rate. Objective: To evaluate prescription errors in the prescriptions processed at the outpatient pharmacy of the Naval Medical Center during the period from January to March 2021. Methodology: This is an applied study with a deductive method and an observational, retrospective, cross-sectional design. A data collection form was used to analyze a sample of 336 prescriptions from a population of 2,700 prescriptions processed at the outpatient pharmacy of the Naval Medical Center during the period from January to March 2021. The evaluation was carried out by analyzing 16 indicators grouped into four dimensions: patient data, prescriber data, medication data, and legibility. Results: The percentages of errors were 9.38%, 18.82%, 47.27%, and 38.99% for the dimensions of patient data, prescriber data, medication data, and legibility, respectively. Conclusion: The prescriptions processed at the outpatient pharmacy of the Naval Medical Center during the period from January to March 2021 presented errors in all prescriptions analyzed.
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Errores de prescripción en las recetas médicas atendidas en el servicio de farmacia del Policlínico Municipal de Santa Anita. Lima 2021
(Universidad Privada Norbert Wiener, 2021-08-06) Grijalva Fernandez, Alicia Silvia; Justil Guerrero, Hugo Jesús
Prescribing errors are frequent, leading to medication misuse and jeopardizing patients' health restoration. The objective of this study was to evaluate prescribing errors in medical prescriptions filled at the pharmacy service of the Santa Anita Municipal Polyclinic. For this, an observational, cross-sectional, and basic study was conducted. The sample consisted of 255 medical prescriptions, and a data collection form adapted by the researcher was used. The percentage of prescriptions with errors in prescriber data was 7.1%. The percentage of prescriptions with errors in patient data was 73.7%, with the most prominent being in the gender indicator (64.7%) and diagnosis (31%). The percentage of prescriptions with errors in medication data was 34.5%, with the most prominent being in the concentration (19.2%), the INN (International Nonproprietary Name) (16.5%), and the route of administration (9.4%). The percentage of prescriptions with errors in legibility was 7.5%. It is concluded that there is a high percentage of prescribing errors in the patient data dimension, which demonstrates a failure to complete all required data on the medical prescription.
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Errores de prescripción en recetas médicas atendidas en Farmacia Universal sede Lima Cercado – 2020
(Universidad Privada Norbert Wiener, 2021-08-02) Quispe Herrera, Carina Inés; Justil Guerrero, Hugo Jesús
The difficulty in writing medical prescriptions is a worldwide problem. A prescription is a legal health document that includes pharmacological or non-pharmacological directions and must be legible. Timely error detection will prevent negative effects on patient health. The objective of this study was to determine prescribing errors in medical prescriptions filled at the Farmacia Universal, Cercado de Lima branch, in 2020. Methodology: The method was deductive-synthetic, with a quantitative approach. The research type was basic, with a descriptive research level and a descriptive, observational-cross-sectional design. The sample consisted of 359 medical prescriptions, and a checklist was used for data collection. Results: The results determined that 72.14% of evaluated prescriptions had prescribing errors. Specific errors were identified: illegible handwriting (33.1%); errors related to prescriber data (78.27%); errors related to patient information (97.8%); errors related to medication data (51.3%); and errors related to therapeutic indications (96.1%). Prescription dates were present in 72.7% and absent in 27.3%. Validity dates were present in 1.7% and absent in 98.3%. Conclusion: 72.14% of the evaluated prescriptions had prescribing errors.
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Errores de prescripción y características de medicamentos en recetas atendidas de la oficina farmacéutica del distrito de Pillco Marca en Huánuco 2021
(Universidad Privada Norbert Wiener, 2022-07-07) Mamani Pocohuanca, Liliana Lizeth; Justil Guerrero, Hugo Jesús
The objective was to describe prescribing errors and medication characteristics in prescriptions filled at the pharmaceutical office in the Pillco Marca district, Huánuco, in 2021. Methods: A quantitative, descriptive, and cross-sectional approach was used. The technique was observation, and the instrument was a checklist applied to 357 prescriptions. The data were analyzed using descriptive statistics presented in tables and figures. Results: Compliance for patient data on prescriptions was 56.6%, for medication data it was 79.5%, and for prescriber data it was 63.3%. The predominant medication family was antibiotics (59.9%), with the most common route of administration being oral (53.8%) and the most frequent pharmaceutical form being syrup (36.4%). Conclusion: The most common prescribing errors identified were those with three errors per prescription, accounting for 26% of cases and involving patient, medication, and prescriber data.
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Errores de prescripción y dispensación de medicamentos a pacientes hospitalizados con COVID-19 en el Hospital Nacional Arzobispo Loayza, agosto–diciembre 2020
(Universidad Privada Norbert Wiener, 2021-08-02) Chumbipuma Chumberiza, Annie Aleyda; Huamani Flores, Hilda; Justil Guerrero, Hugo Jesús
Objective: To determine the relationship between medication prescribing and dispensing errors in hospitalized COVID-19 patients at the Arzobispo Loayza National Hospital, from August to December 2020. Materials and methods: This research is a basic study with a correlational design and a quantitative approach. The sample consisted of 377 medical prescriptions (therapeutic sheets and their respective care records) filled at the Hospitalization Pharmacy service. An observational and documentary analysis technique was used, applying a previously validated checklist as the instrument to include indicators for the two study variables. Results: Prescription errors were found in 17.5% of cases, with illegibility being the most frequent at 52.2%. Inadequate compliance with medication dispensing was 19.4%, with the reception and validation of the prescription showing the highest non-compliance at 34.8%. For the hypothesis test, a bilateral significance value of less than 0.05 was found (p=0.000), leading to the acceptance of the alternative hypothesis and the rejection of the null hypothesis. A strong positive correlation was also found (Phi Coefficient = 0.919). Conclusion: A significant relationship was determined to exist between medication prescribing and dispensing errors in hospitalized COVID-19 patients at the Arzobispo Loayza National Hospital from August to December 2020.
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Errores en la medicación de pacientes y grupo profesional de salud en el área de Medicina Interna de la Clínica Internacional sede San Borja de abril 2020–marzo 2021.Lima 2021
(Universidad Privada Norbert Wiener, 2021-08-05) Mejía Fernández, Edith del Rocío; Izquierdo Santillan, Abigail; Justil Guerrero, Hugo Jesús
Medication Errors (MEs) that occur during the medication utilization process and involve healthcare professionals in the hospital setting constitute a relevant clinical problem that poses a risk to patient safety, making preventative measures necessary. The objective of this study was to evaluate the relationship between patient MEs and the healthcare professional group in the internal medicine area of the Clínica Internacional, San Borja branch, from April 2020 to March 2021. The research was applied type, with an observational, cross-sectional design. A data collection form was used. The population was 2,446 Medical Prescriptions (MPs), and the sample was 333 randomly selected prescriptions, analyzed with a 95% confidence level. Results: The relationship between patient MEs and the healthcare professional group showed 5.7% in prescribing errors committed by the surgeon, followed by 4.2% in administration committed by the licensed nurse, and 1.8% in dispensing committed by the pharmacy assistant, pharmaceutical chemist assistant, and pharmacy technician. Conclusion: The most relevant relationship between patient MEs and the healthcare professional group in the internal medicine area of the Clínica Internacional, San Borja branch, was found in prescribing errors committed by surgeon doctors.
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Evaluación de las prescripciones médicas e interacciones medicamentosas en recetas relacionadas a COVID-19 atendidas en dos establecimientos de boticas Mifarma de los distritos de Comas y Los Olivos, Junio a Setiembre del 2020
(Universidad Privada Norbert Wiener, 2022-05-26) Mosquera Condor, Astrid Carolina; Aguilar Espinoza, Katherin Yajhaira; Justil Guerrero, Hugo Jesús
The objective of this research was to evaluate good prescribing practices (GPP) and identify drug interactions in prescriptions related to COVID-19. The methodology was deductive and quantitative, with a basic-exploratory research type and a non-experimental design. The study included 542 medical prescriptions related to COVID-19. Results: It was found that 7.01% of the prescriptions complied with GPP. The compliance for medication data was highest at 80.81%, followed by prescriber data at 34.31%, and patient data at 7.01%. A total of 54 drug interactions were identified. The most common interactions were: enoxaparin-dexamethasone (62), enoxaparin-ceftriaxone (59), azithromycin-hydroxychloroquine (57), aspirin-dexamethasone (29), enoxaparin-paracetamol (28), aspirin-levofloxacin (26), warfarin-dexamethasone (24), and warfarin-azithromycin and warfarin-ivermectin (23). Of all interactions, 60.5% were pharmacodynamic and 39.5% were pharmacokinetic. By onset, 5 were rapid, 24 were slow, and 25 were unknown. By severity, 8 were major, 33 were moderate, and 13 were minor. Conclusion: A low percentage of compliance with GPP was found. The lack of an established treatment guide for COVID-19 resulted in many of the medications used to mitigate patients' signs and symptoms causing a greater number of drug interactions.
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Eventos supuestamente atribuibles a la vacunación o inmunización (ESAVI) y características de las vacunas contra el COVID-19 en adultos del distrito de San Isidro 2022
(Universidad Privada Norbert Wiener, 2022-06-10) Muñoz Sanchez, Breysson Mijail; Trevejo Rodriguez, Karen Cinthya; Justil Guerrero, Hugo Jesús
Objective: To identify the Adverse Events Following Immunization (AEFI) and characteristics of COVID-19 vaccines in adults in the San Isidro district in 2022. Methodology: This was a quantitative, deductive, analytical, applied, and non-experimental study. The technique was observation, and the instrument was a survey applied to 382 patients. The data were analyzed using descriptive statistics presented in tables and figures. Results: The findings showed that for local reactions, 86% reported a mild reaction at the injection site, while for somatic reactions, 89% presented a mild reaction. Regarding the type of vaccine, 41.6% indicated they received the AstraZeneca vaccine, and 59.4% received the third dose. For pre-existing conditions, 77.2% had no prior illnesses, aside from stress (7.6%), diabetes (5.0%), and hypertension (2.9%). Conclusion: It was identified that 87.5% of the Adverse Events Following Immunization (AEFI) from COVID-19 vaccines in adults in the San Isidro district in 2022 were of a mild nature.