Examinando por Autor "Llalle Marín, Alexander"

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Effectiveness of losartan plus hydrochlorothiazide in managing hypertension in patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2018-09-28) Llalle Marín, Alexander; Panduro Saavedra, Eyder; Calsin Pacompia, Wilmer
Objective: Analyze and systematize the evidence on the effectiveness of losartan plus hydrochlorothiazide in the management of hypertension in patients with Chronic Kidney Disease. Methods: This study is quantitative, the study design is a systematic review, the population constituted by the bibliographic review of 18 scientific articles of which only 10 articles make up the sample, the data collection was carried out through bibliographic review of both international and national research articles whose primary topic was the effectiveness of losartan plus hydrochlorothiazide in the management of hypertension in patients with Chronic Kidney Disease. RESULTSIt is concluded that of 100%, 30% correspond to Japan, 20% to the USA and 10% to Mexico, 10% to Malaysia, 10% to Argentina and 20% to China. These results demonstrated that the combination of Losartan/Hydrolorothiazide has an excellent safety profile. However, the combination of high-dose losartan and hydrochlorothiazide significantly decreased serum uric acid concentration after 3 months of treatment in all cases. Conclusions: it is concluded that 9 of the related studies on the effectiveness of losartan plus hydrochlorothiazide in the management of hypertension in patients with Chronic Kidney Disease have favored the remission of the disease, were very well tolerated and there was an optimal response for improvement. 1 concludes that both the treatment of losartan in monotherapy and hydrochlorothiazide in combined therapies were effective, because no advantage was evident between them.