Examinando por Autor "Lovera Tataje, Maria Nicolasa"
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Publicación Acceso abierto Identificación de interacciones medicamentosas potenciales en recetas médicas atendidas en la farmacia ambulatoria del Hospital Carlos Lanfranco La Hoz, periodo setiembre–noviembre 2018(Universidad Privada Norbert Wiener, 2019-03-06) Lovera Tataje, Maria Nicolasa; Herencia Torres, Victor ReynaldoThe objective of this study was to identify potential drug interactions in medical prescriptions filled by the psychiatry service at the outpatient pharmacy of the Carlos Lanfranco La Hoz Hospital from September to November 2018. A retrospective, descriptive, and cross-sectional study was conducted, in which information was collected from medical prescriptions. The study population consisted of 450 medical prescriptions filled by the psychiatry service after applying inclusion and exclusion criteria. The study found that out of the 450 validated prescriptions, 226 had potential drug interactions, for a total of 248 interactions. By gender, 136 (60.2%) were for female patients and 90 (39.8%) for male patients. The prescriptions with the most potential drug interactions were sertraline-clonazepam (50 cases, 20.16%), risperidone-fluoxetine (25 cases, 10.8%), and risperidone-clonazepam (16 cases, 6.5%). According to the mechanism of action, 96 (38.7%) interactions were pharmacokinetic, and 152 (61.3%) were pharmacodynamic. In terms of severity, the interactions were moderate (208 cases, 83.9%), major (40 cases, 16.1%), and minor (0 cases, 0%). Based on documentation type, 16 (6.5%) were excellent, 210 (84.7%) were good, and 22 were fair or poor. This study highlights the importance of identifying drug interactions to prevent health problems related to medication use and to seek the patient's well-being and improvement.
