Examinando por Autor "Martin Flores, Dina Isabel"
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Ítem Acceso abierto Effectiveness of the use of probiotics for the prevention of necrotizing enterocolitis and mortality in preterm infants(Universidad Privada Norbert Wiener, 2018-07-08) Martin Flores, Dina Isabel; Rondón Zorrilla, Susy Zulema; Perez Siguas, Rosa EvaObjective: To systematically analyze the evidence on the efficacy of probiotics for the prevention of necrotizing enterocolitis and mortality in preterm newborns. Material and method: Eleven scientific articles on the efficacy of probiotics for the prevention of necrotizing enterocolitis and mortality in preterm newborns were found in the databases Cochrane, Scielo, Lilacs, and Medline/Pubmed. A systematic review was applied, analyzing the studies using the GRADE scale to verify their strength and quality of evidence. Of the 11 articles reviewed, 36% (4/11) correspond to the methodological design of systematic reviews, 55% (6/11) are meta-analyses, and 9% (1/11) is a systematic review and meta-analysis. Results: 82% (9/11) demonstrate the efficacy of probiotics for the prevention of necrotizing enterocolitis and mortality in preterm newborns, and 18% (2/11) show that probiotics prevent only necrotizing enterocolitis. Conclusions: From the 11 articles reviewed, the efficacy of probiotics for the prevention of necrotizing enterocolitis and mortality in preterm newborns is evidenced.Ítem Acceso abierto Efficacy of the use of probiotics for the prevention of necrotizing enterocolitis and mortality in premature newborns.(Universidad Privada Norbert Wiener, 2018-07-08) Martin Flores, Dina Isabel; Rondón Zorrilla, Susy Zulema; Perez Siguas, Rosa EvaObjective: Systematize the evidence on the effectiveness of oral lactoferrin for the prevention of necrotizing enterocolitis and sepsis in preterm newborns. Materials and Methods: This systematic review consists of 10 scientific articles found on the effectiveness of oral lactoferrin for the prevention of necrotizing enterocolitis and sepsis in preterm newborns, found in the following databases: Lipecs, Lillacs, Scielo, Chrocane, Medline, and Pubmed. Among the evidence, we found experimental research designs, meta-analyses, and systematic reviews, with the articles published in Spanish and English, and no older than ten years. Results: Of the 10 articles reviewed, 90% (9/10) show that the administration of oral lactoferrin in preterm newborns, with very low birth weight and neonates, decreases late-onset sepsis and necrotizing enterocolitis. 10% (1/10) does not show the effectiveness of oral lactoferrin in preterm newborns. Conclusion: The effectiveness of oral lactoferrin for the prevention of necrotizing enterocolitis and sepsis in preterm newborns is evident.
