Examinando por Autor "Mauricio Olivera, José Alejandro"

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    Utilidad de pruebas inmunocromatográficas clínicas para detección de antígeno prostático específico aplicadas en muestras forenses de hisopados vaginales. Unidad Médico Legal II Lima Este, 2021-2022
    (Universidad Privada Norbert Wiener, 2023-06-22) Mauricio Olivera, José Alejandro; Casana Jara, Kelly Milagritos
    For the analysis of Prostate Specific Antigen (PSA), the objective of the present study was to evaluate the usefulness of the clinical inmunochromatographic tests (PIC) ECOTEST, CTK BIOTECH and MONTEST in detecting PSA in forensic samples of vaginal swabs taken as evidence in cases of crimes against sexual freedom in the Legal Medical Unit II Lima East; 2021-2022. The research design is non-experimental, applied, cross-sectional, descriptive and comparative. Fifty vaginal swabs were analyzed; each swab was subjected to the seminal fluid recovery technique and inoculated in the wells of the ECOTEST, CTK BIOTECH and MONTEST ICP cassettes. The BLUESTAR Identi-PSA forensic immunochromatographic test (PIF) was considered as a reference test (gold standar). Similar excellent results were obtained for the three ICPs (ECOTEST, CTK-BIOTECH and MONTEST): Sensitivity of 100% (CI 95%=98.98%-100%), Specificity of 100% (CI 95%=97.62%-100%), Validity Index of 100% (CI 95%=99.00%-100%), Positive Predictive Value (PPV) of 100% (CI 95%=98.28%-100%), Negative Predictive Value (NPV) of 100% (CI 95%=97.62%-100%). Similar statistical results were also obtained for the three PICs: Youden Index with a value of 1.00, ROC Curve with an AUC =1.00 at 95% CI; and Cohen's Kappa Indices with a value of 1.000 and 0.000 standard error. Concluding the significant usefulness of ICP for the detection of PSA in forensic vaginal swab samples.