Examinando por Autor "Menacho Flores, Rosario Nora"

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    Critical review: effect of omega-3 supplementation on the reduction of symptoms of arthralgia in adult women with breast cancer
    (Universidad Privada Norbert Wiener, 2024-06-20) Menacho Flores, Rosario Nora; Bohórquez Medina, Andrea Lisbet
    Omega-3 fatty acids play a role in nutritional treatment due to their therapeutic effect on cancer, mainly because of their anti-inflammatory properties, and should be incorporated into the diet. Patients undergoing hormone therapy with aromatase inhibitors for hormone-positive breast cancer are more likely to experience arthralgia, leading to early treatment interruption. The objective was to determine the effect of Omega-3 supplementation on improving arthralgia symptoms in these patients. Information was searched on PUBMED, COCHRANE, and SCIENCE DIRECT, finding 32 articles, 10 of which were evaluated using the CASPE critical reading tool. Finally, a systematic review and network meta-analysis were selected, with a level of evidence AI and a strong recommendation grade. The critical discussion concluded that taking Omega-3 polyunsaturated fatty acid (PUFA) supplements, on average 3.3g/day with a 40:20 EPA/DHA ratio for 24 weeks, reduced the worst pain scale, though no significant difference was found compared to placebo or other treatments. The risk of side effects was low in breast cancer patients with arthralgia.