Examinando por Autor "Moreno Exebio, Luis Enrique"

Mostrando 1 - 2 de 2

Acceso abierto
Características, procedencia y lugares de incautación de los productos farmacéuticos y productos sanitarios falsificados en Lima – Perú 2016–2019
(Universidad Privada Norbert Wiener, 2021-11-08) Marcatoma Tumbalobos, Nataly; Cervantes Tenorio, Samy Jazmin; Moreno Exebio, Luis Enrique
The objective of this research was to determine the characteristics, origin, and places of seizure of counterfeit pharmaceutical and sanitary products in Lima, Peru, from 2016 to 2019. Method: A data collection form was used, with data taken from alerts issued by the General Directorate of Medicines, Supplies, and Drugs. Results: The percentage of counterfeit pharmaceutical and sanitary products was 27% in 2016, 36% in 2017, 5% in 2018, and 32% in 2019. The district with the highest prevalence of seizures was Cercado de Lima (70.4%). The origin of both seized pharmaceutical products (97.3%) and sanitary products (99.4%) was non-healthcare establishments. According to the Anatomical Therapeutic Chemical (ATC) classification, the most prevalent groups of counterfeit medications were the musculoskeletal system (29%), respiratory system (18%), and digestive system and metabolism (15%). The most counterfeited dosage form was tablets (51%). The most prevalent seized sanitary products were cosmetics (96.2%). Conclusions: The district with the highest number of seizures was Cercado de Lima, and the origin of seized products was non-healthcare establishments. The most frequently seized sanitary products were cosmetics, while the most common pharmaceutical form was tablets. The most counterfeited ATC group was the musculoskeletal system, and branded products had a higher percentage of counterfeiting.
Acceso abierto
Caracterización de interacciones medicamentosas en pacientes hospitalizados con patologías cardiovasculares del "Hospital Nacional Guillermo Almenara Irigoyen – EsSalud", periodo julio–noviembre 2017
(Universidad Privada Norbert Wiener, 2018-08-20) Rodriguez Natividad, Mariela Elizabeth; Tuano Condori, Doris Janeth; Moreno Exebio, Luis Enrique
This study was conducted with the purpose of characterizing drug–drug interactions (DDIs) in hospitalized patients with cardiovascular diseases at the Hospital Nacional Guillermo Almenara Irigoyen – EsSalud between July and November 2017. Data were collected by reviewing medical prescriptions from the clinical records of 139 hospitalized patients with these pathologies. A descriptive, prospective, and longitudinal study design was applied. After applying the selection criteria, 127 patients (91%) were found to present drug–drug interactions. Of these, 101 (73%) were male and 38 (27%) were female; 93 patients (67%) were older than 60 years. Regarding the number of prescribed drugs, 25 patients (18%) were taking six medications. Antiplatelet agents (acetylsalicylic acid and clopidogrel) accounted for 192 prescriptions (39.2%). According to the type of interaction, 48 (20%) were pharmacokinetic and 197 (80%) pharmacodynamic; the most frequent association was clopidogrel–enoxaparin, with 39 cases (15.9%). Potential interactions were identified in 245 cases (98.8%) and actual interactions in 3 cases (1.2%). With respect to the time of occurrence, 71 interactions (29%) were classified as late, while in terms of severity, 166 (68%) were considered severe. The search for drug–drug interactions was performed using the Micromedex, Drug Interaction Checker, and Medscape databases. In conclusion, 67% of the study population were aged 60 years or older and did present drug–drug interactions, the majority of whom were male. Most interactions (81%, n=147) were pharmacodynamic, and among the cardiovascular pathologies, heart failure accounted for 31.4% (n=77) of the cases.