Examinando por Autor "Oscco Huayta, Villiam Anibal"

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    Critical Review: Influence of intestinal microbiota alteration on the development of colorectal cancer.
    (Universidad Privada Norbert Wiener, 2020-12-10) Oscco Huayta, Villiam Anibal; Bohórquez Medina, Andrea Lisbet
    According to the World Health Organization (WHO), cancer is a public health problem. Among them, colorectal cancer has the highest incidence. The present investigation, Influence of the alteration of the intestinal microbiota on the development of colorectal cancer, was developed as a critical review. Objective: Evaluate the scientific literature through a critical reading of it, using the Critical Appraisal Skills Program Spanish (CASPE) tool in published studies. The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in PUBMED, SCIELO, SCOPUS, SCIENCE DIRECT, REDALYC, DIALNET, LILACS, finding 87 articles, selecting 29 that were evaluated by the CASPE critical reading tool, selecting the Systematic Review entitled Preclinical and clinical relevance of probiotics and synbiotics in colorectal carcinogenesis: a systematic review, which has a level of evidence AI and Grade of Recommendation Strong, according to the researcher's expertise. The critical commentary concludes that intestinal dysbiosis influences colorectal carcinogenesis. However, more studies are necessary to identify the characteristics of the eubiosis profile. It is important that new prophylactic, diagnostic and therapeutic strategies be carried out based on research into the intestinal microbiota.