Examinando por Autor "Rivas Altez, Walter"
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Publicación Acceso abierto Características del consumo indiscriminado de la píldora del día siguiente y su relación con la salud de mujeres consumidoras en tres zonas del distrito de San Martín de Porres - Lima - Perú 2022(Universidad Privada Norbert Wiener, 2024-10-16) Mendoza Tapia, Jaisia Yanell; Puertas Carrera, Patricia; Rivas Altez, WalterThis correlational, analytical, cross-sectional research work has been carried out with the objective of determining the characteristics that influence the indiscriminate intake of the morning-after pill in women from three areas of the San Martin de Porres district. The methodology used is the survey and the instruments used were a questionnaire and the previous interview. The population studied was 380 women who took the morning-after pill indiscriminately. The results indicate that the women who mostly ingest the morning-after pill with respect to age are between 21 and 31 years old; Regarding the religion of the consumers, it is revealed that those who profess the Catholic religion have the highest consumption with 84% of the studied population; Likewise, the level of education corresponds to women with secondary education with 75%; With respect to the employment situation, it is associated that women with independent jobs are the ones with the highest consumption, making up 52% of the population studied; In marital status, it was observed that single women mostly use the morning-after pill with 43%, followed by cohabiting with 28%, married with 26%. Regarding the intake of the morning-after pill and together with other hormonal contraceptives in tablets, it was observed that 90% used it together, one of the reasons for multiple intakes indicates that 38% did so because they forgot the pill. classic contraceptive pill, 30% and 15% indicated that it was due to insecurity of the contraceptive method and due to the ingestion of liquor, assuming the ineffectiveness of the traditional contraceptive method respectively. Regarding health manifestations, 32% reported menstrual irregularity with intermittent bleeding, 20% reported breast pain, anxiety 8%, weight gain 6%, and headaches 18% respectively. Regarding the bleeding manifested, it was observed that 55% had two or fewer bleedings per month, two to four bleedings per month, 23%, bleeding for more than 10 days, 15% manifested bleeding. The behavioral changes were observed: 43% showed instability or nervousness, embarrassment 36%, irritability 30%, feeling of fear or fear 16%. It is concluded that the intake of the morning-after pill is related to the health of female consumers, whether due to repetitive intake or not; likewise, its consumption is related to the sociodemographic and individualized factors specific to women.Publicación Acceso abierto Determinación del uso de misoprostol en auto abortos y sus consecuencias en la salud de mujeres consumidoras en tres zonas de la provincia constitucional del Callao – Perú 2023(Universidad Privada Norbert Wiener, 2025-03-27) Soto Salcedo, Benilda Rosa; Uvaque Gaytan, Janeth Kelly; Rivas Altez, WalterThis descriptive, analytical, and cross-sectional research was conducted to determine how the factors that intervene in the self-medication of the drug misoprostol by women who attend three pharmaceutical establishments in the constitutional province of Callao are related, as well as to analyze the consequences at the health level, taking into consideration parameters such as socioeconomic status, sociodemographic status, and individual perceptions of women. The methodology used in the present study was the Survey, using an instrument validated by expert judgment such as the questionnaire. The results obtained reveal that within the sociodemographic parameters studied, 44% of the interviewees are women aged 35 years or older, with a frequency of 66, followed by women aged 26 to 30 years with 21.33%. 84.96% are Catholic; 49.335 and 44.67% correspond to secondary and higher education levels respectively; Likewise, 46% are women in a state of cohabitation and 36.67% are single women, 34.67% are women who have independent jobs and housewives have a frequency of 20.67% and women with university studies with 14% respectively, the use of misoprostol in relation to gestation time was approximately 2 months with 46.67%, abdominal pain was one of the most frequent effects being 51.33% and nausea with 30% respectively, hemorrhage was one of the complications that the interviewees had being 52.67%, with respect to the possible sequelae product of self-abortion, they stated having recurrent infections at the level of the reproductive system being 18% of the interviewees as well as deterioration of sexual desire and pleasure with 12% and psychological problems of 10% respectively. Statistics show that there is a close relationship between the variables age and the consequences of using misoprostol, where the Chi Square, p reveals p=0.009 indicating a close statistical relationship.Publicación Acceso abierto Factores asociados a la falta de adherencia al tratamiento farmacológico en afecciones respiratorias agudas e influencia a la automedicación en usuarios que asisten a tres establecimientos farmacéuticos del distrito de San Juan de Lurigancho, Lima – Perú. 2024(Universidad Privada Norbert Wiener, 2025-08-11) Quiroz Suarez, Mabel; Velarde Auccasi, Marlene; Rivas Altez, WalterEl presente trabajo de investigación de tipo analítico, correlacional, transversal cuyo objetivo fue determinar los factores que intervienen en la falta de adherencia al tratamiento farmacológico de afecciones respiratorias agudas así como la influencia a la automedicación sobre la enfermedad respiratoria en pacientes que acuden a tres establecimientos farmacéuticos de distrito de San Juan de Lurigancho. La metodología utilizada en el estudio fue la encuesta así como uso de un cuestionario debidamente validado por juicio de expertos. La muestra corresponde a 380 usuarios encuestados que acudieron a tres los establecimientos farmacéuticos. Los resultados indican que el 36% de los encuestados tienen edades comprendidas entre 45 y 50 años y que no cumplen con la adherencia al tratamiento farmacológico, seguido de 32% entre las edades de 21 a 30 años, con respecto al sexo existe predominio por el sexo femenino, siendo 71,05% de la población estudiada, el 58,16% corresponde a personas con estudios superiores seguido de 36,58% con educación secundaria, el 36,05% labora como independiente, y los de trabajo dependiente con 28,95%; con respecto a la adherencia se obtuvo que el 69,47% compran los medicamentos de forma fraccionada y ello contribuye a la falta de adherencia, el 67,63% indicó que no consume el medicamento a la hora indicada, el 78,68% suspende su medicación por encontrar mejoría, el 62,89% manifestó problemas digestivos; con respecto a la automedicación se observó que las edades comprendidas entre 21 a 30 años se automedicó, representando 31,3% y las edades entre 41 a 50 años corresponde a 36,3% donde aplicando la estadística Chi cuadrado revela que existe una relación estadística siendo p=0,000. Con relación al sexo el sexo femenino representa 71,1% y masculino 28,9% donde al aplicar el Chi cuadrado se obtuvo un valor 9.0 p=0.003<0.05 donde existe relación estadística. Así mismo se realizó el Test de Morisky Green a los datos sociodemográficos donde se obtuvo relaciones estadísticas significativas.Publicación Acceso abierto Formulación de fármaco por nueva vía de administración: Closantel Sódico, gel antiparasitario de uso veterinario contra Fasciola hepática(Universidad Privada Norbert Wiener, 2015) Zegarra Cárdenas, Diana; Rivas Altez, WalterThe study was carried out with the purpose of formulating a medicine through a new route of administration of sodium closantel gel for veterinary use against Fasciola hepatica during the months of January to April 2015. An experimental, analytical, cross-sectional research work was conducted to elaborate a gel that meets the optimal conditions for use as an antiparasitic, taking into account the ideal physicochemical processes for the formulation of the gel in question. It should be noted that the physicochemical processes are important in the elaboration of the gel, with the fundamental basis being the interaction of the appropriate excipients, the active ingredient, adequate quantity, etc. Several excipients were considered for the preparation of the gel, finding that the use of Cremophor in different amounts is not suitable for the gel formulation. The use of Tween 80, which is employed for viscosity, is also not suitable for the gel formulation as it presented non-ideal characteristics. Poligel was used for the formulation of the gel, and incompatibilities and inconsistencies were found (Not suitable). Formula 1012 was used, in which it was observed that the use of 80 g is adequate for the gel formulation (Suitable). A formula with codification 1012 was also used, where the ideal temperature for the formulation of the gel is 70°C. The use of Polyethylene glycol in an amount of 200 mL is adequate for the formulation of the gel. In the search for alcohols for the gel formulation it was found that: the use of rectified ethanol alcohol in an amount of 100 mL is suitable, alcohol coded (1013) in an amount of 100 mL is suitable, alcohol coded (1014) in an adequate amount of 200 mL, and formula coded (1015) in an amount of 15 mL is suitable. The use of Monoethanolamine in an amount of 8.5 mL is optimal for the gel formulation. It should also be noted that the active ingredient sodium closantel does not present any inconvenience in the formulation of the gel.Publicación Acceso abierto Impacto de la farmacovigilancia y la gestión de reacciones adversas al fluconazol en la cadena de boticas Farmacia Universal, Lima 2025(Universidad Privada Norbert Wiener, 2025-11-05) Martínez Ocaña, Lizbeth Pamela; Purisaca Quispe, Jonathan Gregory; Rivas Altez, WalterThe present study had the Objective: To determine the impact of pharmacovigilance on the management of adverse reactions to fluconazole in the Farmacia Universal pharmacy chain, Lima 2025. Methodology: The research was developed under a quantitative at a correlational level, with a non-experimental, cross-sectional design. The population consisted of 250 collaborators in pharmacy functions, of whom 161 workers in direct customer care, available at the time of the study, were surveyed. For data collection, a Likert-type questionnaire was applied, validated by expert judgament and with high reliability according to Cronbach’s Alpha coefficient. Results: The results showed a positive and significant correlation between the pharmacovigilance system and the management of adverse reactions to fluconazole (r=0.707; p=0.000). Continuous staff training (r=0.633) and participation in reporting processes (r=0.653) were directly associated with better identification, recording, and monitoring of adverse drug reactions. Likewise, institutional barriers (r=0.664), mainly related to the avilability of resources and organizational culture, were identified as limiting efficiency of the system. Conclusions: It is concluded that pharmacovigilance constitutes a fundamental axis to ensure patient safety and the rational use of antifungical drugs in community pharmacies. The findings support the need to strengthen training programs, implement standardized reporting protocols, and promote a culture of active notification, which Will have an impacto on the optimization of internal processes and on the generation of scientific evidence useful for public health in Perú.Publicación Acceso abierto Incidencia del uso de benzodiacepinas en casos de supuestos delitos contra la libertad sexual realizados en la Dirección de Criminalística de la Policía Nacional del Perú, año 2021(Universidad Privada Norbert Wiener, 2023-02-03) Rivera León, Daniela Alicia; Rojas Vega, Angélica María; Rivas Altez, WalterThis research aimed to determine the incidence of benzodiazepine use in alleged sexual freedom crimes reported at the Criminalistics Directorate of the Peruvian National Police in 2021. The method employed was deductive, with a quantitative approach, basic type, and non-experimental, cross-sectional, and descriptive design. A total of 1,017 toxicological expert reports meeting the inclusion criteria were analyzed. The technique used was document analysis, and the data collection tool was a data collection sheet. Results: The findings showed the incidence of crimes against sexual freedom during 2021, with a high number of reported cases involving females, within the age range of 18 to 25 years, originating from police stations in downtown Lima. Intermediate-acting benzodiazepines were the most commonly used substances in cases of sexual assault. Conclusion: There is a high incidence of benzodiazepine use in alleged sexual freedom crimes reported at the Criminalistics Directorate of the Peruvian National Police in 2021.Publicación Acceso abierto Metamidofos y carbofurano en uvas (Vitis vinifera) de tres mercados de Lima Metropolitana. 2025(Universidad Privada Norbert Wiener, 2026-02-03) Chirinos Pajuelo, Diego Alejandro; Rivas Altez, WalterEl presente estudio tuvo como objetivo determinar la concentración de plaguicidas prohibidos como Metamidofos, carbofurano entre otros en uvas (Vitis vinifera) de mercados de Lima Metropolitana, 2025. La metodología se basó en la extracción QuEChERS y el análisis por cromatografía líquida acoplada a espectrometría de masas en tándem (LC-MS/MS). Aunque el objetivo inicial se centró en Metamidofos y Carbofurano, el análisis se extendió a otros tres agroquímicos prohibidos: Clorpirifos, Monocrotofos y Metomilo, encontrándose al menos uno de ellos en 3 mercados muestreados. Los resultados obtenidos evidencian la presencia de los plaguicidas Metamidofos y carbofurano en uvas a la concentración 0.005 y 0.006 mg/kg respectivamente. Estos hallazgos evidencian una contaminación generalizada que incumple la normativa peruana y representa un grave riesgo para la salud pública debido a la exposición dietética a una mezcla de neurotóxicos, asimismo se reportaron resultados como Metomilo (hasta 0.39 mg/kg) y Monocrotofos (hasta 0.041 mg/kg), superando los Límites Máximos de Residuos (LMR) de la Comisión Europea. El mercado Mayorista de Comas y el Mercado Mayorista de Puente Piedra, presentaron la mayor carga de contaminantes en muestras de uvas. Como conclusión se evidencia que existen fallas sistémicas de control y fiscalización en el comercio local de uvas.Publicación Acceso abierto Síntomas de intestino irritable con relación al uso de plantas medicinales en adultos mayores de 30 años que acuden al Mercado Señor de Los Milagros, Ventanilla 2025(Universidad Privada Norbert Wiener, 2025-08-05) Arril Herrera, Dayanne Rutt Soledad; De La Cruz Santos, Lady Ivonne; Rivas Altez, WalterThe objective of the study was to determine the relationship between irritable bowel symptoms and the use of medicinal plants in adults over 30 years of age who attend the Señor de los Milagros Market, Ventanilla 2025. Method. The study was cross-sectional, non-experimental design, correlational scope, hypothetical-deductive method, quantitative approach, basic type study, sample 162 adults over 30 years of age, through surveys and use of questionnaires the data was collected, hypothesis was contracted with Spearman's Rho. Results. 38.3% were between 51- 60 years old, 46.9% were overweight or obese; in irritable bowel symptoms; 43.8% presented abdominal pain, 51.2% abdominal distension, 40.1% presented diarrhea or constipation, 50.6% improved with the use of medicinal plants; 21.6% presented fatigue or general malaise, 27.2% improved with the use of medicinal plants. Chamomile was used by 49.4%, peppermint by 47.5%, plantain by 25.3%, fennel by 16.7%, and ginger by 28.4%. 40.1% had little knowledge of the side effects. It was effective for 50.6% of patients with abdominal pain, 46.9% with abdominal bloating, 42% with diarrhea and/or constipation, and 54.3% with much lower cost than conventional medications. A moderately significant relationship (p=0.000; rho=.0458) was observed between irritable bowel symptoms and the use of medicinal plants. Conclusion: There is a moderately significant positive relationship between irritable bowel symptoms and the use of medicinal plants in adults over 30 years of age.
