Examinando por Autor "Sánchez Saavedra, Solange Zulema"

Seleccione resultados tecleando las primeras letras
Mostrando 1 - 1 de 1
  • Miniatura
    ÍtemAcceso abierto
    Oral cryotherapy as non-pharmacological treatment for the prevention of oral mucositis in patients with cancer chemotherapy
    (Universidad Privada Norbert Wiener, 2019-02-05) Sánchez Saavedra, Solange Zulema; Cerdán Calderón, Yolanda Mary; Avila Vargas Machuca, Jeannette Giselle
    Systematic review of 10 scientific articles on the efficacy of oral cryotherapy in preventing chemotherapy-induced oral mucositis, retrieved from databases such as Lilacs, Scielo, Medline, and Pubmed, and analyzed using the GRADE scale to determine the strength and quality of evidence. Results: Ten articles were analyzed, of which 50% were randomized controlled trials, 20% retrospective reviews, 20% systematic reviews, and 10% experimental studies. All articles (100%) concluded that oral cryotherapy is effective in reducing the incidence and severity of chemotherapy-induced mucositis, with 50% effectiveness for 5-fluorouracil chemotherapy and 50% for melphalan chemotherapy. Conclusions: Oral cryotherapy administered before, during, and after bolus 5-fluorouracil and high-dose melphalan administration in patients undergoing autologous stem cell transplantation is effective in reducing the incidence and severity of oral mucositis. No effectiveness was demonstrated with other cytostatics such as methotrexate and edrexate.