Examinando por Autor "Soto Huaccanqui, Maria Marlene"

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    Effectiveness of isoniazid in preventing tuberculosis in patients with the human immunodeficiency virus
    (Universidad Privada Norbert Wiener, 2020-01-05) Soto Huaccanqui, Maria Marlene; Meneses Canchari, Yda Marlene; Pérez Siguas, Rosa Eva
    Objective: Systematize the evidence on the effectiveness of isoniazid in preventing tuberculosis in patients with HIV. Methodology: Systematic Review is a research design that allows us to collect and synthesize the best scientific evidence regarding a study topic. Of the studies, 6 are systematic reviews and 7 are cohort reviews. Results: We found 13 relevant studies. 90% (12) report that IPT is effective and they are from the United States, England, Tanzania, Australia and Brazil; while 10% (1) of the United States report that it is not effective in preventing tuberculosis in patients with HIV. Within these studies it was also found that the administration of isoniazid in children is 90% effective, if isoniazid is administered for 36 months compared to 6 months it is much more beneficial in patients with HIV, 6 months of isoniazid in patients with HIV reduces the risk of tuberculosis during the 7 years of follow-up, one of the reasons why a patient stops taking isionazid is the liver effects and the lack of follow-up for the IPT. Conclusions: It is concluded that the majority reports that the use of isonicide is effective in preventing tuberculosis in patients living with HIV; also that chemoprophylaxis with isionazide is important because it helps us reduce cases of tuberculosis in patients living with HIV; Therefore, it also reduces HIV/TBC mortality cases.