Examinando por Autor "Vásquez Quispe, Ángel David"

Seleccione resultados tecleando las primeras letras
Mostrando 1 - 1 de 1
  • Miniatura
    PublicaciónAcceso abierto
    Efecto antiinflamatorio y analgésico del extracto etanólico de la cáscara Inga feuillei DC. "pacay" en ratones
    (Universidad Privada Norbert Wiener, 2022-02-18) Vásquez Quispe, Ángel David; Villacorta Antón, Santos Enrique; Chávez Flores, Juana Elvira
    In Peru, there are various medicinal plants with therapeutic benefits; the plant species Inga feuillei comes from northern Peru (La Libertad - Trujillo). Objective: This study aims to demonstrate the anti-inflammatory and analgesic effect of the ethanolic extract from the peel of Inga feuillei DC, 'pacay,' in mice. Methods: To evaluate the anti-inflammatory effect, 42 rats were divided into 7 groups of 6, and the subplantar edema method described by Winter was used. To evaluate the analgesic effect, 42 mice were divided into 7 groups of 6, and the Koster et al. method was used. Results: The ethanolic extract from the 'pacay' peel showed its greatest analgesic effect at a concentration of 300 mg/kg (87.7%), surpassing the standards of Paracetamol 500 mg/kg (42.8%) and tramadol (86.4%). The greatest anti-inflammatory effect was at a concentration of 500 mg/kg (42.8%), an effect comparable to the standards of Ibuprofen 400 mg/kg and Dexamethasone 4mg/kg. Conclusion: The analgesic and anti-inflammatory effects of the ethanolic extract from the peel of Inga feuillei DC were demonstrated in mice.