Examinando por Autor "Vasquez-Elera, Luis E."

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Factors Associated with Mortality in Patients with COVID-19 from a Hospital in Northern Peru
(MDPI, 2023-03-23) Valladares-Garrido, Mario J.; Alvarez-Risco, Aldo; Vasquez-Elera, Luis E.; Valdiviezo-Morales, Christopher G.; Martinez-Rivera, Raisa N.; Cruz-Zapata, Annel L.; Pereira-Victorio, César Johan; Garcia-Peña, Elian; Failoc-Rojas, Virgilio E.; Del-Aguila-Arcentales, Shyla; Davies, Neal M.; Yáñez, Jaime A.
We aimed to identify the factors associated with mortality in patients with COVID-19 from the hospitalization service of the Cayetano Heredia Hospital, Piura, Peru, from May to June 2020. A prospective study was conducted in hospitalized patients with a confirmed diagnosis of COVID-19 through serological and/or molecular reactive testing. The dependent variable was death due to COVID-19, and the independent variables were the epidemiological, clinical and laboratory characteristics of the patient. The chi-square test and the non-parametric Mann–Whitney U test were used, with a significance level of 5%. Of 301 patients with COVID-19, the majority of them were male (66.1%), and the mean age was 58.63 years. Of the patients analyzed, 41.3% of them died, 40.2% of them were obese and 59.8% of them had hepatic steatosis. The three most frequent signs/symptoms were dyspnea (90.03%), fatigue (90.03%) and a cough (84.72%). Being an older adult (p = 0.011), being hospitalized in the ICU (p = 0.001), overweight (p = 0.016), obese (p = 0.021) and having compromised consciousness (p = 0.039) and thrombocytopenia (p = 0.024) were associated with mortality due to COVID-19. Overall, the mortality rate due to COVID-19 was 41.3%. Having an older age, being hospitalized in the ICU, overweight, obese and having compromised consciousness and thrombocytopenia were positively associated with mortality in patients with COVID-19. These findings highlight the need to establish an adequate system of surveillance and epidemiological education in hospitals and communities in the event of new outbreaks, especially in rural and northern Peru.
Acceso abierto
Factors Associated with Mortality in Patients with COVID-19 from a Hospital in Northern Peru
(MDPI, 2023-02-23) Valladares-Garrido, Mario J.; Alvarez-Risco, Aldo; Vasquez-Elera, Luis E.; Valdiviezo-Morales, Christopher G.; Martinez-Rivera, Raisa N.; Cruz-Zapata, Annel L.; Pereira-Victorio, César Johan; Garcia-Peña, Elian; Failoc-Rojas, Virgilio E.; Del-Aguila-Arcentales, Shyla; Davies, Neal M.; Yáñez, Jaime A.
We aimed to identify the factors associated with mortality in patients with COVID-19 from the hospitalization service of the Cayetano Heredia Hospital, Piura, Peru, from May to June 2020. A prospective study was conducted in hospitalized patients with a confirmed diagnosis of COVID-19 through serological and/or molecular reactive testing. The dependent variable was death due to COVID-19, and the independent variables were the epidemiological, clinical and laboratory characteristics of the patient. The chi-square test and the non-parametric Mann–Whitney U test were used, with a significance level of 5%. Of 301 patients with COVID-19, the majority of them were male (66.1%), and the mean age was 58.63 years. Of the patients analyzed, 41.3% of them died, 40.2% of them were obese and 59.8% of them had hepatic steatosis. The three most frequent signs/symptoms were dyspnea (90.03%), fatigue (90.03%) and a cough (84.72%). Being an older adult (p = 0.011), being hospitalized in the ICU (p = 0.001), overweight (p = 0.016), obese (p = 0.021) and having compromised consciousness (p = 0.039) and thrombocytopenia (p = 0.024) were associated with mortality due to COVID-19. Overall, the mortality rate due to COVID-19 was 41.3%. Having an older age, being hospitalized in the ICU, overweight, obese and having compromised consciousness and thrombocytopenia were positively associated with mortality in patients with COVID-19. These findings highlight the need to establish an adequate system of surveillance and epidemiological education in hospitals and communities in the event of new outbreaks, especially in rural and northern Peru.
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Self-medication in hospitalized patients with COVID-19: A cross-sectional study in northern Peru
(European Academy of HIV/AIDS and Infectious Diseases, 2022-03-31) Vasquez-Elera, Luis E.; Failoc-Rojas, Virgilio E.; Martinez-River, Raisa N.; Morocho-Alburqueque, Noelia; Temoche-Rivas, Mario S.; Valladares-Garrido, Mario J.
Introduction This study aimed to identify factors associated with self-medication in patients with COVID-19. Methods A cross-sectional study was conducted using medical records of patients with COVID-19 who self-medicated before admission to a hospital in Piura, Peru. Prevalence ratios and 95% confidence intervals were estimated using generalized linear models with Poisson distribution family, log link function, and robust variance. Results Out of 301 patients, 165 (54.8%) self-medicated before hospital admission, being more frequent self-medication with ivermectin (85.5%) and azithromycin (71.5%). The frequency of self-medication in those aged between 30-59 years was 2.53-fold higher than in those between 18-29 years. Male patients, dyslipidemia, smoking, and hepatic steatosis were associated with self-medication. Clinical characteristics associated with self-medication were fever, cough, headache, anosmia, dysgeusia, nausea/vomiting, and gastroesophageal reflux. Conclusions A high frequency of self-medication before hospital admission was observed in Peruvian patients with COVID-19, mainly of drugs without proven efficacy.