Examinando por Autor "Villacorta Ñaupari, Carlos Martín"

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    Características de las reacciones adversas de los medicamentos antineoplásicos en el servicio de oncología, del Hospital Nacional Guillermo Almenara Irigoyen – EsSalud. Febrero–julio del 2015
    (Universidad Privada Norbert Wiener, 2015) Villacorta Ñaupari, Carlos Martín; Torres Veliz, Ernesto Raúl
    The objective of this research was to determine the characteristics of adverse drug reactions (ADRs) associated with antineoplastic agents in the Oncology Service of the “Guillermo Almenara Irigoyen” National Hospital – EsSalud, during the period from February to July 2015. For this study, the antineoplastic drugs available at the Guillermo Almenara Irigoyen National Hospital were considered. Methodology. A prospective descriptive cross-sectional study was conducted. Ninety-two patients diagnosed with cancer and undergoing chemotherapy who met the inclusion and exclusion criteria were analyzed, of which ADRs were detected in 80 patients (87%). These cases were evaluated using the Peruvian Pharmacovigilance Algorithm. Results. The analysis was limited to the 80 patients with ADRs. Male patients presented the highest number of ADRs (70%); the age group of 56–67 years showed 45% of ADRs. The therapeutic subgroup of platinum derivatives accounted for 59% of the total ADRs identified. Nausea (31%) and vomiting (19%) were the most frequent ADRs, and the gastrointestinal system was the most affected (73%). Regarding causality, 77% of ADRs were classified as probable, requiring specific treatment. According to severity, 65% were moderate, and according to the Edwards–Aronson classification, 99% were type A.