Examinando por Autor "Zevallos Flores, Orlando"

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    Factores asociados a la prescripción e interacciones farmacológicas potenciales en pacientes de medicina interna del Hospital Hugo Pesce Pescetto, 2024
    (Universidad Privada Norbert Wiener, 2025-05-02) Dextre Sanchez, Mariela Ines; Zevallos Flores, Orlando; Ñañez del Pino, Daniel
    The objective of this research was to determine the factors associated with prescription and potential pharmacological interactions in internal medicine patients at the Hugo Pesce Pescetto Hospital, 2024. The method was deductive, non-experimental design, cross-sectional, descriptive level or scope, quantitative approach, and basic type. The sample consisted of 180 prescriptions, which were analyzed using the Drugs.com interaction checker, and the information obtained was recorded on an observation sheet. The results showed that, according to the number of medications in the prescriptions, 19.4% involved 2 to 3 medications per prescription, 52.8% involved 4 to 5 medications, 21.7% involved 6 to 7 medications, and 6.1% involved 8 to 10 medications. According to the sociodemographic factor, the most severe interactions were observed in 15.7% of women and 11.4% of men over 60 years old. According to frequency, 63.9% presented 1 to 2 pharmacological interactions, 23.3% had 2 to 5 interactions, 5.6% had 5 to 6 interactions, and 7.2% had 7 to 11 interactions. Regarding the type of interaction, 95.8% were pharmacodynamic and 4.2% pharmacokinetic. The most frequently involved medications were omeprazole (9.9%) and furosemide (6.8%). According to the severity of interactions, 74.9% were of moderate severity, 13.0% were of greater severity, 9.5% were of lesser severity, and 2.2% were contraindicated. It is concluded that there are factors associated with prescriptions that are responsible for drug interactions, with adults being the most affected.