Farmacia y Bioquímica
URI permanente para esta comunidadhttps://hdl.handle.net/20.500.13053/33
Navegar
Examinando Farmacia y Bioquímica por Línea de Investigación "Salud, enfermedad y ambiente"
Mostrando 1 - 9 de 9
- Resultados por página
- Opciones de ordenación
Ítem Acceso abierto Antimicrobial effect of remineralizing toothpastes against streptococcus mutans – In Vitro study, Lima 2020.(Universidad Privada Norbert Wiener, 2020-12-28) Lazaro Diego, Miriam Luz; Céspedes Porras, JacquelineThe objective of this study was to evaluate the antimicrobial effect of two remineralizing toothpaste formulations compared to a fluoride toothpaste against the ATTCC 25175 strain of Streptococcus mutans through microbiological tests. An in vitro experimental design was used to observe the antimicrobial effect of three toothpaste formulations: Group 1 with a nanocomplex of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP), Group 2 with Hydroxyapatite, and Group 3 with Fluoride. The inhibition halos were measured using the disk diffusion method (Kirby-Bauer method) on agar plates previously inoculated with the bacterial strain at 24 and 48 hours. Twenty samples were analyzed per group, and the data were recorded in a previously validated data collection form. Results: The two remineralizing toothpaste formulations, Group 1 with CPP-ACP and Group 2 with Hydroxyapatite, showed antimicrobial effects against the ATTCC 25175 strain of Streptococcus mutans at 24 hours, with mean inhibition halos of 12.60 and 11.65, respectively. At 48 hours, antimicrobial effects were observed in all three groups, with mean inhibition halos of 12.80 for Group 1, 12.0 for Group 2, and 10.20 for Group 3. A significant difference was found between the two measurements for all groups (p=0.000, p<0.05). Conclusion: All three toothpaste formulations evaluated exhibited antimicrobial effects against the ATTCC 25175 strain of Streptococcus mutans at 48 hours, with the remineralizing pastes showing slightly superior effects.Ítem Acceso abierto Dry socket and its relationship with working time in patients treated in the dental area of the FAP Las Palmas hospital during the second quarter of 2019.(Universidad Privada Norbert Wiener, 2020-12-22) Portella Tuesta, Carlos Renzo; Ascanoa Olazo, Jimmy AntonioAn observational, retrospective, cross-sectional, and correlational study was conducted with a descriptive level. The population consisted of 257 adult patients aged 18 to 61 years who visited the FAP Las Palmas Hospital during the second quarter of 2019. A data collection form was used to record age, gender, quadrant of simple extraction, work time in minutes, and the presence of dry socket at the follow-up date. The results showed that 4.7% of the patients developed dry socket. It was concluded that dry socket had a statistically significant relationship with the work time in patients treated in the dentistry area of FAP Las Palmas Hospital during the second quarter of the year 2019.Ítem Acceso abierto Knowledge and Attitudes about COVID-19 in Norbert Wiener University Dental Students in 2020.(Universidad Privada Norbert Wiener, 2020-12-07) Torres Hastahuamán, Carla Sandra; Céspedes Porras, JacquelineObjective: The aim of this study was to determine the level of knowledge and attitudes towards COVID-19 among dental students at a private university during the pandemic. Methodology: A quantitative approach was used, applying a descriptive and cross-sectional design. The sample consisted of 256 preclinical and clinical students who were administered a questionnaire virtually via Google Forms. Prior to its application, the instrument was validated through expert judgment and a pilot test, achieving a Cronbach's Alpha reliability coefficient of 0.81. Results: The findings indicated that 67.2% of the students had a moderate level of knowledge about COVID-19. Regarding their attitudes towards COVID-19, although 84.8% felt more likely to get infected and transmit the virus to their families, 78.5% believed that COVID-19 had impacted their university education, 92.6% felt the need to acquire more knowledge on the subject, and 79.7% reported positive attitudes towards the impact of the disease on their educational and professional life. Conclusion: The majority of the students displayed a moderate level of knowledge about the disease and reported positive attitudes towards the impact of the disease on their educational and professional life.Ítem Acceso abierto PH and salivary flow in the health personnel of a hospital emergency service after the consumption of carbonated and milk drinks. Callao 2020.(Universidad Privada Norbert Wiener, 2020-12-07) Castañeda Machado, Esther; Vilchez Bellido, DinaThe objective of the study was to determine the pH and salivary flow in healthcare personnel from an emergency hospital service after the consumption of carbonated and dairy beverages in Callao, 2020. The sample consisted of 43 healthcare professionals from the emergency hospital service, whose basal pH and post-ingestion pH at 5, 15, and 30 minutes were recorded, as well as salivary flow before and after beverage consumption. The research type was quasi-experimental, prospective, longitudinal, and descriptive. Data were recorded on a form and later analyzed statistically using SPSS software 21.0, including paired T-test, one-way ANOVA, and repeated measures ANOVA with a significance level of p<0.001. Results showed that the average pH in healthcare personnel before consuming carbonated and dairy drinks was 6.83 ±0.38. The average basal volume and volume/minute were 3.88±1.48 and 0.77±0.29 respectively, showing a tendency to be symmetric, with values detailed according to the type of drink. Comparing the change in volume and vol/min between drink type and basal value, all cases showed an increase, which was significant (p<0.001). Additionally, final volume and vol/min values among the four drinks did not show a significant difference (p=0.47 and p=0.29, respectively). pH values at 5, 15, and 30 minutes also showed differences between groups (p<0.001), with a tendency towards an increase in pH value. It is concluded that salivary pH decreased and salivary flow volume increased in healthcare personnel from an emergency hospital service after consuming carbonated and dairy beverages; however, only dairy beverages returned to their initial pH, while carbonated drinks, particularly Coca Cola, did not recover their pH within the determined time.Ítem Acceso abierto Playful teaching strategy on care for pediatric dental care during the coronavirus pandemic in primary school children of the San Vicente Ferrer educational institution, Lima 2020.(Universidad Privada Norbert Wiener, 2020-12-29) Quispe Chávarry, Verónica Yanina; Céspedes Porras, JacquelineObjective: This research aimed to determine the effectiveness of an audiovisual playful teaching strategy on dental care for pediatric patients during the coronavirus pandemic among a group of primary school students. A quantitative, descriptive, cross-sectional study was designed. The sample consisted of 151 schoolchildren aged 8 to 11. Results: Before the educational intervention, 69.5% of the schoolchildren achieved a High level of knowledge, and 30.5% a Medium level; these scores improved by 12% after watching the video, with 81.5% of the schoolchildren reaching the High level. There was no statistically significant relationship between the level of knowledge obtained before and after the intervention with gender (p=0.724) or age (p=0.920). The paired T-test showed that the application of the audiovisual playful strategy was effective in improving knowledge about dental care for pediatric patients during the coronavirus pandemic among the observed schoolchildren (t=5.884, p=0.000). Conclusion: The audiovisual playful strategy was effective in enhancing the understanding of dental care among primary school students during the pandemic.Ítem Acceso abierto Pouch-type incision and triangular incision and its postoperative effect in extractions of retained third molars in patients treated at the dental clinic of the Norbert Wiener private university, Lima 2016 _ 2017.(Universidad Privada Norbert Wiener, 2020-12-02) Canales Ramos, Miguel Angel; Ascanoa Olazo, Jimmy AntonioThe purpose of this research was to compare the postoperative effects (edema, trismus) in the extraction of retained lower third molars between the pouch incision and triangular incision types, as well as to assess postoperative edema and trismus on the seventh day after the extraction. This in situ study was observational, longitudinal, prospective, and comparative. Thirty patients treated at the Norbert Wiener Private University clinic were analyzed, divided into two groups of 15 patients each, where the different incision types were performed. The first step in the study was to take measurements prior to the surgical procedure. Subsequently, the extraction, including wound closure through suturing, was observed. Patients were then scheduled for a follow-up appointment seven days after the surgery for suture removal and final measurements. The results showed no statistically significant differences in edema and trismus between the pouch incision and the triangular incision. It was concluded that there are no differences in the postoperative effects of retained lower third molar extractions between the pouch and triangular incision types.Ítem Acceso abierto Prevalence of the short lingual frenulum in newborns in their first pediatric dentistry consultation at the National Maternal Perinatal Institute of Lima in the period 2017-2019.(Universidad Privada Norbert Wiener, 2020-12-30) Cerna Corcuera, Keyssy Geovanni; Arauzo Sinchez, Carlos JavierObjective: To determine the prevalence of short lingual frenulum in newborns during their first pediatric dental consultation at the National Maternal Perinatal Institute of Lima-Peru in the period 2017-2019. Materials and Methods: Observational study, with a descriptive, retrospective longitudinal design. The population consisted of a sample of 1,408 newborns with their respective pediatric dental records. Results: The prevalence of short lingual frenulum in our population during 2017-2019 was 20.6% of infants. We also found that 8.2% (2017), 7.8% (2018), and 4.6% (2019) of infants had a short lingual frenulum. The incidence of short lingual frenulum in boys and girls was 3.86% over the years 2017-2019. The incidence rate was 2.16 per thousand births in 2018 and 1.70 per thousand births in 2019. The presence of the short lingual frenulum was more prevalent in males, infants whose gestational period was full-term. From 2017-2019, it was found that 50% of infants with a short lingual frenulum underwent frenectomy. Conclusions: The prevalence of the short lingual frenulum is low and has been decreasing each year, but an evaluation of the oral cavity should still be performed in the first months of life.Ítem Acceso abierto Relationship of body mass index and loss of taste in Covid-19 patients in Servimedic health program services, Lince – 2020.(Universidad Privada Norbert Wiener, 2020-12-18) Lope Alderete, Yudit; Araujo Farje, Jessica JazminThe objective of this research was to determine the relationship between Body Mass Index (BMI) and taste loss in COVID-19 patients at Servimedic Health Programs Services, Lince. This research employed a scientific method with a quantitative approach, being observational, documentary, analytical, retrospective, cross-sectional, and explanatory in nature. It included 148 laboratory-confirmed COVID-19 patients. Data was collected from the Servimedic database between June and September. The Chi-square test was used for data analysis. The results showed that 41.9% of COVID-19 patients had overweight and taste loss, while 9.5% had overweight without taste loss, revealing a statistically significant relationship (p≤0.05). Of the total patients, 51.4% had overweight, 29.7% had normal BMI, and 18.9% were obese. Of the total patients, 73.6% experienced taste loss, while 26.4% did not. According to BMI and sex, 51.4% of overweight patients were 12.2% female and 39.2% male. By age and BMI, 51.4% had overweight, 14.2% were aged 18 to 29, 33.8% were aged 30 to 59, and 3.4% were aged 60 and above. Regarding taste loss by sex, 73.6% of patients had taste loss, with 23.6% being female and 50.0% male. By age, 25.0% of patients with taste loss were aged 18 to 29, 45.9% were aged 30 to 59, and 2.7% were aged 60 and above. It was concluded that Body Mass Index is significantly related to taste loss in COVID-19 patients.Ítem Acceso abierto Resistance to fracture of fluid and bulk-type resins in comparison to conventional resins. in vitro study. Lima Perú. 2020.(Universidad Privada Norbert Wiener, 2020-12-29) Collao Huerta, Oscar Pablo Cesar; Adrianzen Acurio, César AugustoObjective: To determine the fracture resistance of flowable and bulk-fill resins compared to conventional resins. Methodology: Three types of resins were used: a conventional resin, a flowable resin, and a bulk-fill resin, each shaped into cylinders with dimensions of 8 millimeters in height and 4 millimeters in diameter. The sample size was determined by sample calculation, using 10 resin cylinders of each type, which were subjected to compression by a universal testing machine. This machine applied a compressive force on the resin cylinders at a rate of 1 mm/min of compression until the cylinders fractured. Data processing was carried out using SPSS software with the ANOVA statistical test. Results: It was found that the fracture resistance of conventional resin was 149.879 ± 18.609 Megapascals, the fracture resistance of the flowable resin was 122.994 ± 26.906 Megapascals, and the fracture resistance of the bulk-fill resin was 122.994 ± 26.906 Megapascals. Conclusion: The flowable resin exhibited higher fracture resistance than the conventional resin, and the latter showed greater resistance than the bulk-fill resin.