Examinando por Materia "Acne Vulgaris"
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Publicación Acceso abierto Actividad antibacteriana de los extractos hidroalcohólicos de las hojas, flores, tallo y raíz de Schkuhria pinnata (Lanm.) Kuntze ex Thell. “canchalagua” frente a Propionibacterium acnes(Universidad Privada Norbert Wiener, 2018-03-13) Purizaca Meléndez, Kevin Manuel Eduardo; Condori Antialon, Laura Isabel; Félix Véliz, Luis Miguel VisitaciónThe plant species Schkuhria pinnata (Lanm.) Kuntze ex Thell, “Canchalagua,” from the city of Ayacucho, was obtained at the Wholesale Market “La Parada,” district of La Victoria – Lima, and was subsequently taxonomically classified at the Natural History Museum of the Universidad de San Marcos. The sample was cleaned and dried at the Research Center of the Universidad Norbert Wiener, where the parts of the plant—stem, root, leaves, and flowers—were separated. Hydroalcoholic extracts of each part were prepared, and the phytoconstituents present were identified, such as flavonoids, reducing sugars, phenolic compounds, and carbohydrates. For the microbiological test, the Disk Diffusion method was used with blood agar medium and the Propionibacterium acnes strain (ATCC® 11827). Standard antibiotics Q.P.: Doxycycline, Levofloxacin, Azithromycin, and Penicillin were employed. Disks impregnated with 10 µL of the hydroalcoholic extracts were added and compared with the standard antibiotic disks on the plates, showing that the hydroalcoholic extract of the leaves presented the largest inhibition halo diameter.Publicación Acceso abierto Factores asociados a la adherencia al tratamiento con isotretinoina en pacientes con acné vulgaris del hospital de la Solidaridad del distrito de Puente Piedra. Lima. 2025(Universidad Privada Norbert Wiener, 2025-06-04) Manchay Alberca, Santos Maria; Santos Alvarado, Milagros Ana; Bustamante Fustamante, Flor LidiaObjective: This study aimed to determine the factors associated with adherence to isotretinoin treatment in patients with acne vulgaris at the Hospital de La Solidaridad in the Puente Piedra District, Lima, in 2025. Methodology: This was a basic study with an observational design, a quantitative approach, a correlational level, and a cross-sectional cut. A survey was conducted with 100 patients attending the Hospital de La Solidaridad in Puente Piedra in 2025, using two instruments. Results: A total of 62% of patients had severe acne, and 70% had suffered from it for less than a year. The most common adverse effects of isotretinoin were headaches (reported by 64% of patients) and lip dryness (reported by 63%). Although patients had good knowledge about the disease, more than 50% were non-adherent to the treatment. Additionally, 95% received pharmaceutical care, ensuring proper dispensing practices in compliance with Good Dispensing Practices (GDP). Conclusion: It was determined that adherence to isotretinoin treatment in patients with acne vulgaris at the Hospital de La Solidaridad in the Puente Piedra District was associated with various factors, including socioeconomic conditions, pharmacotherapy-related aspects, the pharmaceutical professional, and the disease itself. On the other hand, patient-related factors (such as knowledge) did not show a significant relationship with adherence during 2025.Publicación Acceso abierto Perfil hormonal e índice de masa corporal en mujeres perimenopaúsicas con acné vulgar. Centro Médico Dozone medicina biológica. Lima, 2020(Universidad Privada Norbert Wiener, 2022-07-06) Ormachea Flores, Carmen Cecilia; Benites Castillo, Santiago MoisesAcne vulgaris that occurs during adulthood, involves a series of pathophysiological alterations, which in the specific case of women is largely due to the hormonal alterations typical of this stage and generates a great physical, psychological, emotional and in the quality of life. Objective: To analyze the hormonal profile and Body Mass Index in perimenopausal women with acne vulgaris treated at the Dozone Biological and Alternative Medicine Medical Center, Lima, 2020. Methodology: The research method is quantitative, for its purpose it is applied and according to its scope it is descriptive -correlational. The sample consisted of 200 perimenopausal women who met the inclusion criteria. The technique used was documentary observation and the data collection sheet was used as an instrument. Results: the most frequent alterations that appear in the hormonal profile are observed in the estradiol concentration and mainly the FSH / LH ratio is altered. 79.50% of the women are overweight and 10% have grade I obesity. Regarding the sociodemographic characteristics, the ages of 45 to 49 years stand out. The clinical characteristics of acne vulgaris in perimenopausal women are that 48.50% of lesions correspond to comedones and 21.50% to pustules; the most frequent locations are the face in 42.50%, the beginning of the neck in 21.50% and the chin in 17%. The degree of severity of acne vulgaris in perimenopausal women is severe in 44%. There is a highly significant relationship between alterations in estradiol concentration and the degree of acne severity, as well as a significant relationship between the FSH / LH ratio and the degree of severity. There is a significant relationship between the Body Mass Index and the degree of severity of acne vulgaris, with overweight and obese women having severe and moderate acne in most cases.Publicación Acceso abierto Uso de fórmulas magistrales en pacientes dermatológicos que acuden a la farmacia universal Cercado de Lima 2023(Universidad Privada Norbert Wiener, 2024-07-12) Astucuri Alarcon, Andrea Danitza; Chilingano Lima, Hans Alexéi; Llahuilla Quea, José AntonioThe objective of this study was to analyze the use of compounded medications in dermatological patients attending the Farmacia Universal in Cercado de Lima in 2023. The methodology employed was a deductive, quantitative, applied approach, with an observational, non-experimental, and cross-sectional design. A total of 420 prescriptions were analyzed, representing a population of dermatological prescriptions from the Farmacia Universal in Cercado de Lima. Data were collected using a data collection form. The results showed that, according to age, the highest frequency was found in the 30-59 age range (46.7%), and the most frequent sex was female (56.2%). Of the 420 prescriptions, the highest percentage of active ingredients was 10% urea, representing 7.2% of the total 1080 active ingredients. Furthermore, the pharmaceutical form The most frequent prescription is the cream, representing 51%, and for facial use it represents 51.4%. Furthermore, the most frequent diagnosis is acne, representing 20% of a total of 420 prescriptions. It was concluded that users of compounded medications are in the 30-59 age range, with a greater predominance of females. The active ingredient, 10% urea, and the pharmaceutical form, cream, were the most frequently prescribed. The indication was for the face, and the most frequent diagnosis was acne.
