Examinando por Materia "Aminoácidos"

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    Critical review: effect of protein restriction and addition of keto-amino acids in improving renal function in adult patients with stage 3 and 4 chronic kidney disease (CKD)
    (Universidad Privada Norbert Wiener, 2022-04-19) Bellido Vallejo, Milagro; León Cáceres, Johanna del Carmen
    The objective was to identify the effects of protein restriction and addition of keto-amino acids on the improvement of renal function in adult patients with chronic kidney disease in stages 3 and 4. The clinical question was: Is protein restriction and addition of keto-amino acids Will amino acids improve kidney function in adult patients with chronic kidney disease in stages 3 and 4? The Evidence-Based Nutrition methodology was used. The information search was carried out in PUBMED, SCOPUS, WOS, Elsevier, Springer, finding 27 articles, 08 being selected that have been evaluated by the CASPE critical reading tool, finally selecting the Randomized Clinical Trial titled: “Effect of essential amino acids ketoanalogs and protein restriction diet on morphogenetic proteins (FGF-23 and Кlotho) in patients with disease chronic kidney disease in stages 3b-4: a randomized pilot study”, which has a level of evidence I and Grade of Recommendation “Strong”, according to the expertise of the researcher. The critical commentary allowed us to conclude that supplemented protein restriction (LPD) with ketoanalogues of essential amino acids (KA) improves the renal function of adult patients with CKD in stages 3 and 4, making its application recommended to delay the progression of CKD.