Examinando por Materia "Blood Sedimentation"

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Design of procalcitonin versus markers used for the diagnosis of bacterial sepsis in patients at the Intensive Care Unit of the National Hospital Alberto Sabogal Sologuren, 2015
(Universidad Privada Norbert Wiener, 1905-07-07) Gonzales Vasquez, Jose Marino; Hilario Velasquez, Flor Eduvines; Baltodano Honores, Carlos Alberto
Introduction: Diagnosing sepsis in the Intensive Care Unit remains a major challenge, as it can lead to death due to multiple organ failure. Procalcitonin is a marker used to differentiate bacterial infections from inflammatory processes of other etiologies. The aim of this study was to determine the performance of procalcitonin compared to other markers used to diagnose bacterial sepsis in the Intensive Care Unit of the National Alberto Sabogal Sologuren Hospital in 2015. Methodology: The study was descriptive, comparative, non-experimental, prospective, and cross-sectional. Results: 30 patients from the Intensive Care Unit of the National Alberto Sabogal Sologuren Hospital, with a presumptive diagnosis of sepsis, were studied from January to April 2015. Of these, 26.67% had a positive blood culture, considered the confirmatory test for bacterial sepsis. The performance of the tests was as follows: Procalcitonin (PCT): Sensitivity (S) 87.5%, Specificity (E) 95.45%, Positive Predictive Value (PPV) 87.5%, Negative Predictive Value (NPV) 95.4%. For C-reactive protein (CRP): S 100%, E 0%, PPV 26%, NPV 0%. For the Erythrocyte Sedimentation Rate (ESR): S 100%, E 4.76%, PPV 27.58%, NPV 100%. For white blood cell count: S 75%, E 50%, PPV 35.2%, NPV 84.6%. For neutrophil percentage: S 100%, E 15.78%, PPV 29.63%, NPV 100%. Conclusion: Procalcitonin showed better performance for diagnosing bacterial sepsis compared to other markers used currently in the hospital.