Examinando por Materia "Body Fluid Compartments"
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Ítem Acceso abierto Effectiveness of albumin treatment versus other fluids in patients with sepsis(Universidad Privada Norbert Wiener, 2018-07-08) Benito Castro, Elizabeth Maria; Norabuena Granda, Marina Alejandra; Calsin Pacompia, WilmerObjective: To analyze and systematize the evidence on the effectiveness of albumin treatment versus other fluids in patients with sepsis. Materials and Methods: The design is a systematic review, using the GRADE system. The search was conducted in the following databases: Cochrane, Web of Science, OvidSP, PubMed, clinicaltrials.gov, controlled-trials.com, Medline, Elsevier, Web of Science, Embase. The population consisted of 10 articles, including systematic reviews and study samples. Four studies are clinical trials, three are systematic reviews and meta-analyses, and three are meta-analyses only. Results: Of all the studies, 60% demonstrate the effectiveness of albumin as an intravascular volume expander, decreasing the risk of renal failure, pulmonary edema levels, and significantly reducing extravascular pulmonary water. 30% demonstrate the effectiveness of other fluids as the first line in fluid resuscitation due to their market accessibility. 10% demonstrate the effectiveness of both albumin and other fluids in increasing left ventricular stroke work and systolic volume. Conclusions: Of the 10 articles, 6 demonstrate the effectiveness of albumin in patients with sepsis by reducing mortality rates, 3 demonstrate that other fluids are more effective than albumin because it showed no change in mortality, and 1 demonstrates that both albumin and other fluids are effective in increasing cardiac index.Ítem Acceso abierto Effectiveness of albumin treatment versus other fluids in patients with sepsis(Universidad Privada Norbert Wiener, 2018-07-08) Benito Castro, Elizabeth Maria; Norabuena Granda, Marina Alejandra; Calsin Pacompia, WilmerObjective: To analyze and systematize the evidence on the effectiveness of albumin treatment versus other fluids in patients with sepsis. Materials and Methods: The design is a systematic review, using the GRADE system. The search was conducted in the following databases: Cochrane, Web of Science, OvidSP, PubMed, clinicaltrials.gov, controlled-trials.com, Medline, Elsevier, Web of Science, Embase. The population consisted of 10 articles, including systematic reviews and study samples. Four studies are clinical trials, three are systematic reviews and meta-analyses, and three are meta-analyses only. Results: Of all the studies, 60% demonstrate the effectiveness of albumin as an intravascular volume expander, decreasing the risk of renal failure, pulmonary edema levels, and significantly reducing extravascular pulmonary water. 30% demonstrate the effectiveness of other fluids as the first line in fluid resuscitation due to their market accessibility. 10% demonstrate the effectiveness of both albumin and other fluids in increasing left ventricular stroke work and systolic volume. Conclusions: Of the 10 articles, 6 demonstrate the effectiveness of albumin in patients with sepsis by reducing mortality rates, 3 demonstrate that other fluids are more effective than albumin because it showed no change in mortality, and 1 demonstrates that both albumin and other fluids are effective in increasing cardiac index.
