Examinando por Materia "Candida"

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Acceso abierto
Determinar las variaciones anuales y perfil de resistencia de cepas fúngicas aisladas de muestras clínicas antes y durante la pandemia Covid-19, Hospital EsSalud Abancay-Apurímac 2018-2023
(Universidad Privada Norbert Wiener, 2025-12-03) Leguia Gutierrez, Judith Rosemery; Champa Guevara, César Alfonso
Introducción: Los sistemas de salud se transformaron en la pandemia COVID-19, causando cambios que afectaron la vigilancia de infecciones bacterianas y fúngicas en todo el mundo. En ese sentido, muchas especies pueden haber cambiado su epidemiologia. Nuestro objetivo fue determinar las variaciones anuales y perfil de resistencia de cepas fúngicas aisladas a partir de muestras clínicas recolectadas en el periodo previo a la pandemia de COVID-19 y durante el tiempo que esta se desarrolló en el Hospital de EsSalud en la ciudad de Abancay-Apurímac entre el 2018 al 2023. Metodología: Es un analisis observacional retrospectivo donde se analizaron 4610 muestras clínicas referidas para cultivo fúngico del Servicio de Microbiología. Fueron incluidos resultados de pacientes de ambos sexos, con infecciones superficiales/sistémicas y con registro en el sistema de reportes del hospital. Los datos se analizaron mediante registros físicos/digitales (CIE-10), se estandarizaron en Excel y analizaron con SPSS v24. Resultados: Del total se identificaron 226 (4.9%) cultivos positivos. La positividad pre-pandemia (2018–2019) fue 13.3% (43/303), reduciéndose a 1.3–1.8% en 2020–2021, post-pandemia (20.4–47.8% en 2022–2023) registrándose una variación significativa entre periodos del estudio (p=0.011). Entre 2018–2019, Trichophyton mentagrophytes (21.4%), Trichophyton tonsurans (30.4%) el más frecuente, mientras que entre 2020–2021, predominó Candida sp. (33.3–100%). Entre 2022–2023, Trichophyton tonsurans (26.1–39.8%) e informes no específicos de "hifas y levaduras" (29.6%) fueron los más frecuentes. No se registraron datos de resistencia antifúngica. Conclusiones: Se evidenció variaciones anuales en la resistencia fúngicas aisladas, las cuales se manifestaron al comparar los aislamientos obtenidos en el periodo previo a la pandemia por COVID-19.
Acceso abierto
Factors associated with complications after insertion of invasive catheters
(Universidad Privada Norbert Wiener, 1905-07-09) Bulnes Reyna, Marcela Estela; Mantilla Lara, Carmen Isabel; Gómez Gonzales, Walter Edgar
Objective: Establish the factors associated with complications after insertion of invasive catheters. Material and Method: Observational and retrospective systematic review, the search has been restricted to articles with full text, and the selected articles were subjected to a critical reading, using Jover's evaluation to identify their degree of evidence. Results: The population was made up of the bibliographic review of 02 systematic reviews and 08 scientific articles published and indexed in scientific databases, no older than five years and that respond to articles published in Spanish, we found that 20 % (02) correspond to Chile, with 30% (03) we find Spain, while with 10% (05) we find Washington, Wisconsin, Brazil, Mexico and Costa Rica respectively. Most of the quantitative, transversal, experimental and quasi-experimental studies have been studied with 80%, mainly in the countries of Costa Rica, Brazil, Mexico and Spain. Among systematic reviews we find the country of Chile and Wisconsin, with 20%. Conclusions: Among the factors associated with complications we found in 80% of the studies high blood pressure, condition of the catheter, sex, obesity, diabetes mellitus, as for the pathologies according to the studies found were pneumonia, neonatal sepsis, meningitis and perinatal asphyxia; The most frequently found microorganisms were Staphylococcus coagulase (-), Pseudomona sp. and Candida sp. and that greater education of health professionals decreases the incidence of primary bloodstream infections and a substantial decrease in the patient's health care costs.
Acceso abierto
Level of knowledge and application of the antifungigram in invasive candidiasis by clinical laboratory medical technologists, Metropolitan Lima, 2021
(Universidad Privada Norbert Wiener, 2022-11-06) Huamani Anca, Julia Nelly; Guadalupe Gómez, Haydee Ana
Antifungal resistance by Candida sp. yeast in immunocompromised patients and/or those with invasive infections is an emerging problem in public health. Objective: To determine the relationship between the level of knowledge and application of antifungal susceptibility testing in invasive candidiasis, performed by Clinical Laboratory Medical Technologists in hospitals in Lima Metropolitan area. Material and method: A non-experimental, quantitative, cross-sectional, observational study was conducted, surveying 51 Medical Technologists working in the clinical microbiology service. Results: 60.8% worked in the public sector and 39.2% in the private sector; 57.0% had received training on the execution and interpretation of antifungal susceptibility tests; 59.0% were unaware of the epidemiological frequency at their health establishment; 66.7% had a low/regular level of knowledge about antifungal testing; 60.8% applied the antifungal test. Conclusion: A significant relationship exists between the level of knowledge and the application of antifungal testing in invasive candidiasis by Clinical Laboratory Medical Technologists in Lima Metropolitan area (p < 0.005, 95% CI).
Acceso abierto
Susceptibility to Fluconazole and Voriconazole in strains of the genus Candida, isolated in vaginal secretions from patients of reproductive age treated in a Category I-3 Polyclinic, Lima.
(Universidad Privada Norbert Wiener, 2020-10-15) Chanco Lapa, Rocio; Vega Ordinola, Jean Pierre Andrés; Rojas León, Roberto Eugenio
Objective: To determine the susceptibility to fluconazole and voriconazole in strains of the genus Candida, isolated from vaginal secretion of reproductive-age patients treated at a Polyclinic category I-3, Lima.