Examinando por Materia "Cannabis"

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Acceso abierto
Changes in hematological markers after pyrolytic consumption of Cannabis sativa L., in adult users in Lima, 2022
(Universidad Privada Norbert Wiener, 2023-09-03) Botello Izquierdo, Roy Efrain; Moya Salazar, Jeel Junior
Cannabis is a commonly used psychoactive substance, with an estimated 192 million users worldwide. Derivatives of the Cannabis sativa plant are widely used for recreational and medicinal purposes, and its recreational use has become a widely debated topic around the world due to its growing social acceptance and potential impact on public health.
Acceso abierto
Determinación cualitativa de cannabinoides (cannabidiol) en veinte aceites medicinales comerciales obtenidos de pacientes durante consulta médica en Lima, Perú 2021
(Universidad Norbert Wiener, 2023-06-01) Moya Salazar, Milagros del Rosario Marcia; Chávez Flores, Juana Elvira
Este proyecto de investigación tuvo como objetivo: determinar cualitativamente la presencia de cannabinoides (cannabidiol) en 20 aceites medicinales comerciales obtenidos de pacientes durante consulta médica en Lima, Perú 2021. Materiales y métodos: Se diseñó un estudio observacional con enfoque cualitativo y muestreo no probabilístico en el Centro Médico Especializado en Cannabis Medicinal CANNAVITAL en Lima (Perú). Los criterios de inclusión fueron aceites de cannabis procedentes de pacientes con diferentes matrices de aceites, precios, frascos, y con/sin registro sanitario. Se utilizó Fast blue B y el reactivo colorimétrico Reaja para determinar los cannabinoides y cannabidiol (CBD), respectivamente. Resultados: Del total de aceites, 14 (70%) aceites presentaron cannabinoides y que 4 (20%) presentaron concentraciones débiles de cannabinoides. Los aceites con 15 a 20 ml fueron los que tuvieron mayor frecuencia de cannabinoides (n=5, 25%). Además, 9 (45%) aceites presentaron CBD y 1 (5%) aceite tuvo concentraciones débiles. Los aceites con 5 a 10 ml de aceite tuvieron mayores concentraciones de CBD (n=9, 45%). Todos los aceites con matriz de aceite de olivo tuvieron cannabinoides. Conclusiones: la determinación cualitativa de cannabinoides en veinte aceites medicinales comerciales obtenidos de pacientes durante consulta médica en Lima, Perú durante el 2021, demostró que 7/10 aceites contenían cannabinoides en sus diferentes presentaciones comerciales.
Acceso abierto
Effectiveness of the administration of cannabis oil in pediatric patients with refractory epilepsy
(Universidad Privada Norbert Wiener, 2019-10-20) Quispe Gutierrez, Myriam Pamela; Gomez Espiritu, Cecilia del Pilar; Cárdenas de Fernández, María Hilda
Objective: Systematize the evidence on the effectiveness of the administration of cannabis derivatives in reducing seizures in the treatment of patients with refractory epilepsy. Material and Methods: Systematic review meta-analysis, using the GRADE evaluation system to assess the level of evidence, found in the following databases: Pubmed, Pediatrics Official Journal of the AAPS, Scielo, Wiley Online Library. A total of 25 articles were found, but only 10 articles were selected and systematically reviewed. 80% (n = 08/10) of them are systematic reviews, and 20% (n = 02/10) are community-controlled trials. According to the results of the systematic review conducted in this study, the articles come from the countries of Argentina (10%) (n = 01/10), followed by Australia (10%) (n = 1/10), Brazil (10%) (n = 01/10), Canada (20%) (n = 02/10), the USA (30%) (n = 03/10), and Italy (20%) (n = 02/10). Results: Of all the articles found in the systematic review, the use of cannabinoids showed significant effectiveness in the treatment of patients with refractory epilepsy, reducing the number of seizures and improving their quality of life when used as an adjunctive treatment. Conclusion: 100% of the articles used show the effectiveness, in varying degrees, of using cannabinoids for the treatment of drug-resistant epilepsy. However, many of these indicate that further knowledge is needed to accept these results and make them an approved treatment by health authorities worldwide.