Examinando por Materia "Clostridioides difficile"

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Acceso abierto
Effectiveness of probiotics in preventing and controlling antibiotic-induced diarrhea and Clostridium difficile in pediatric patients
(Universidad Privada Norbert Wiener, 2018-12-12) Palma Barrera, Ines Rosario; Millones Gómez, Segundo Germán
Systematic review of 10 scientific articles selected from databases such as Cochrane, LILACS, Scielo, Medline and Pubmed; They were analyzed according to the GRADE scale; resulting in 70% (n=7/10) indicating that probiotics are effective in the prevention and control of diarrhea due to antibiotics and Clostridium difficile in pediatric patients. 60% reduce the risk of developing diarrheal diseases associated with C. difficile. The probiotics S. boulardii and Lactobscyllus rhamnosus are effective in preventing diarrhea due to antibiotics compared to placebos in hospitalized pediatric patients. It is concluded that 7 of 10 reviewed articles show the effectiveness of probiotics for the prevention and control of diarrhea due to antibiotics and Clostridium difficile in pediatric patients.
Acceso abierto
Systematic review "Laboratory Diagnosis in the detection of toxigenic Clostridium difficile in stool samples"
(Universidad Privada Norbert Wiener, 1905-07-09) Salas Cachay, Magaly Tila; Herencia Torres, Victor Reynaldo
Objectives: To establish the effectiveness of microbiological assays for the direct detection of toxigenic Clostridium difficile in stool samples from hospitalized and outpatient patients. Methods: A systematic review was conducted by analyzing 8 databases of studies published in English and Spanish between 2006 and 2016 that evaluate the comparison, description, and prevalence study of this germ and infection caused by Clostridium difficile. A total of 51 articles were found, of which 9 were selected for analysis. Results: Nine descriptive, cross-sectional, case-control studies that used microbiological methods for diagnosis were included. The validity and reliability of the microbiological method for Clostridium difficile were evaluated, and publications from countries such as the United States, Canada, Switzerland, Argentina, Chile, and Peru were found. Conclusion: The availability of these methods has contributed to improving the management of hospitalized and outpatient patients who received antibiotic treatment. This work shows evidence of significant growth and increase in the prevalence of Clostridium difficile infections over different periods. For hospitalized patients, these epidemiological changes require techniques that are well-defined and accessible to all laboratories. Moreover, this method allows for continuous monitoring of patients and helps prevent transmission.