Examinando por Materia "Creatinine"
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Ítem Acceso abierto Correlation between renal profile and the level of glycosylated hemoglobin in patients with diabetes mellitus treated at María Auxiliadora Hospital, 2017(Universidad Privada Norbert Wiener, 2019-03-14) Bautista Borda, Carlos Daniel; Ucañán Vega, Maria Ximena Natividad; Sandoval Vegas, Miguel HernánTransfusion therapy has helped reduce mortality and improve the quality of life for many cancer patients. The objective of this study was to determine the frequency of transfused blood components in patients with neoplastic diseases registered in the Blood Bank service at the Oncosalud Clinic from June 2016 to June 2018. We conducted a retrospective, descriptive, cross-sectional study. We included patients over 18 years old, with preneoplastic alterations, neoplastic diseases, or with recurrences and treatment control, who had received a full, complication-free transfusion. We included 3,022 transfusion requests, of which 1,525 (50.5%) were women with an average age of 59.8±17.5 years, statistically not significant compared to men (65.3±14.1 years) (p=0.210). Both sexes predominantly required red blood cell concentrate (RBC) at 67.9%, followed by platelets (PLT) at 19.9%. The age group from 56 to 70 years demanded the highest amount of blood products (40.2%). In both periods, hematological neoplasms (49.1%) required the highest number of transfusions, followed by gynecological (16.3%) and gastrointestinal (15.1%) neoplasms. This study demonstrated a high frequency of transfused blood components (red blood cell concentrate and platelets), primarily in hematological neoplasms.Publicación Acceso abierto Niveles de transaminasas y creatinina sérica en pacientes con tuberculosis multidrogo resistentes según el tiempo de tratamiento en las RIS de san juan de Miraflores- Lima 2023(Universidad Privada Norbert Wiener, 2024-07-14) Aguina Nelly, Alvarez Ventura; Saldaña Orejón, Italo MoisésLa TB multirresistente es una enfermedad grave y mortal, su tratamiento es cada vez más difícil, la mayoría de los pacientes presentan síntomas relacionados con el hígado y el riñón en poco tiempo. Por ello, el presente estudio de investigación pretende evaluar y conocer los niveles de creatinina sérica y las transaminasas (AST, ALT).Publicación Acceso abierto Relación entre el índice proteína/creatinina y proteinuria 24 de horas para la detección de proteinuria en gestantes de una clínica privada, Lima 2024(Universidad Privada Norbert Wiener, 2025-09-22) Paredes Cieza, Yuly Sthefanny; Borja Velezmoro, Gustavo AdolfoEl estudio tiene como objetivo establecer la relación entre el índice proteína/creatinina y la proteinuria de 24 horas para la detección de proteinuria en gestantes atendidas en una clínica privada en Lima en 2024. Para ello, se empleó una metodología cuantitativa, correlacional e hipotético-deductivo cuya población estuvo conformada por 100 historias clínicas de gestantes, seleccionadas mediante un muestreo no probabilístico por conveniencia entre enero y junio de 2024. Los datos se recopilaron mediante análisis documental de los resultados de laboratorio, aplicando como instrumento a la ficha de recolección de datos. Los resultados indicaron que según IPC, 42% (n=42) de las gestantes presentaron proteinuria mientras que según la recolección de orina de 24 horas, 44% (n=44) presentaron proteinuria. Asimismo la correlacion fue de 0.819 (p< 0.001) con una concordancia de 0.796 (p< 0.001). Además, se identificó un punto de corte óptimo del índice de 0.970 con sensibilidad de 86.4% y una especificidad del 92.86%. Concluyendo que, la correlación fue fuerte, positiva y significativa, siendo el índice una herramienta útil y eficiente para la detección de proteinuria en gestantes.Ítem Acceso abierto Relationship Between Cockcroft-Gault Equations and 24-Hour Urinary Creatinine Clearance in Adults at a Hospital in Callao from January to March 2016(Universidad Privada Norbert Wiener, 2018-09-21) Espinoza Ibañez, Carmen del Rosario; Narro Allende, Jimmy José; Plasencia Vega, César AugustoThe objective was to determine the relationship between the Cockcroft-Gault equations and creatinine clearance in 24-hour urine in adults from a hospital in Callao during the period from January to March 2016. The correlation between these laboratory methods for all patients was moderate, with a significance level lower than the expected significance level. Women aged 18-30 had a weak correlation, women aged 31-64 had a weak correlation, and women aged 65 and older had a weak correlation. Men aged 18-30 had a weak correlation, men aged 31-64 had a moderate correlation, and men aged 65 and older had a moderate correlation. All the cases mentioned showed a significant difference. This study determined a low correlation between the estimated glomerular filtration rate (eGFR) using the Cockcroft–Gault equation and the creatinine clearance equation.Ítem Acceso abierto Serum Concentrations of Glucose, Urea, Creatinine, and Hemoglobin Levels in Elderly Diabetic Adults at a Geriatric Hospital in Lima, 2016(Universidad Privada Norbert Wiener, 1905-07-08) Apagüeño Chistama, Remberto; Sandoval Vegas, Miguel HernánObjective: To determine the serum concentrations of glucose, urea, creatinine, and hemoglobin levels in elderly adults in a geriatric hospital in Lima. Materials and Methods: A selection of 317 elderly patients of both sexes was made. This study is descriptive and prospective, with a non-interventional design. The results were analyzed statistically using descriptive statistics and chi-square tests. According to sex, there was no significant difference between males and females concerning glucose, urea, creatinine, and hemoglobin levels. However, a significant difference was found in the three age groups of elderly adults: those aged 60-74 years (considered advanced age), 75-90 years (considered old or elderly), and those over 91 years (considered very old or extreme elderly). A significant difference in urea levels was found in patients considered elderly and very old. Similarly, there was a significant difference in hemoglobin levels in those considered elderly and very old.Ítem Acceso abierto Urinary Osmolality and Its Relationship with Glomerular Filtration Rate. Laboratory of the National Hospital Hipólito Unánue. Lima 2016(Universidad Privada Norbert Wiener, 1905-07-09) Cruzado Avila, Ivette Johalina; Sandoval Vegas, Miguel HernánThe objective of the study was to determine urinary osmolality and its relationship with glomerular filtration rate (GFR) using the CKD-EPI and MDRD-4 formulas in patients treated at the National Hipólito Unanue Hospital laboratory in Lima, 2016. A total of 184 urine samples meeting the inclusion criteria were selected, with 24-hour urinary osmolality measured and GFR data processed from the hospital laboratory using the Dubois and Dubois body surface area (BSA) formula. GFR was also calculated using the Mosteller and Boyd BSA formulas and the MDRD-4. Results were analyzed using Pearson’s r and Student’s t-test. No correlation was found between GFR or MDRD-4 with urinary osmolality at any stage of chronic kidney disease. A significant difference in osmolality values was observed between stage 1 (GFR >60 mL/min) and the other stages of chronic kidney disease (GFR <60 mL/min). Thus, there was no correlation between osmolality and GFR, but urinary osmolality can be used as an indicator to classify patients with adequate or decreased glomerular filtration.
