Examinando por Materia "Curcumina"

Mostrando 1 - 4 de 4

Acceso abierto
Critical review: effect of curcumin on glycemic and lipid profile in type 2 diabetes mellitus
(Universidad Privada Norbert Wiener, 2023-05-11) Condori Quispe, Elena Yudi; León Cáceres, Johanna del Carmen
Nutritional intervention with curcumin exhibits several physiological and pharmacological properties, such as antioxidant, anti-inflammatory, anticancer, neuroprotective, and antidiabetic activities. This secondary research titled “Critical Review: Effects of Curcumin on the Glycemic and Lipid Profile in Type 2 Diabetes Mellitus” aimed to monitor biochemical parameters through turmeric consumption in type 2 diabetes patients. The Evidence-Based Nutrition (NuBE) methodology was used, and 22 articles were found in PUBMED, MEDLINE, SCIELO, and LILACS, of which 10 were selected for evaluation using the CASPE tool. The selected systematic review and meta-analysis study titled “Potential therapeutic effects of curcumin on the glycemic and lipid profile in uncomplicated type 2 diabetes: a meta-analysis of a randomized controlled trial” has a level II evidence and strong recommendation grade. The critical commentary concluded that hemoglobin A1c, the homeostasis model assessment (HOMA), and low-density lipoprotein (LDL) showed statistically significant reductions in patients treated with curcumin.
Acceso abierto
Critical review: effect of curcumin supplementation on inflammatory indicators of patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2023-10-18) Santi Meléndez, José de Jesús; Bohórquez Medina, Andrea Lisbet
Chronic kidney disease (CKD) is defined as “persistently elevated albumin excretion in urine (≥ 30 mg/g), reduced estimated glomerular filtration rate (eGFR < 60 ml/min/1.73 m2), or both for more than 3 months.” Various studies have shown the effect of curcumin on improving inflammatory indicators in CKD patients. This review aimed to evaluate the effect of curcumin supplementation in CKD patients. The methodology followed the five phases of Evidence-Based Nutrition (NuBE) and databases such as PUBMED, SCIELO, DIALNET, EMBASE, and SCOPUS were used to search for information. Fifteen articles were selected for evaluation using the CASPE critical reading tool, ultimately selecting the systematic review with meta-analysis titled “Efficacy and safety of dietary turmeric supplementation in proteinuria in CKD: a systematic review and meta-analysis of RCTs” with an A I classification – Strong for evidence and recommendation level. The conclusion, based on critical commentary, is that curcumin is useful for proteinuria in CKD patients and could be used as a therapeutic option. However, more research is needed to determine the optimal dose and duration of curcumin treatment.
Acceso abierto
Effect of curcumin supplementation on inflammatory indicators of patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2023-01-19) Jauregui Huaman, Victor Alfredo; Palma Gutiérrez, Edgardo Jhoffire
Some studies have suggested that vitamin D supplementation could be an ally in the treatment of Polycystic Ovary Syndrome (PCOS). The objective of this secondary research was to analyze the effect of vitamin D supplementation on improving the metabolic and hormonal profile of women with PCOS. The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in Pubmed, Plos One, Scielo, Wiley, among others, thus finding 46 articles, 12 being selected, which were evaluated by the CASPE critical reading tool, finally selecting the meta-analysis titled as: “Effect of vitamin D supplementation in polycystic ovary syndrome: A meta-analysis”, which has a level of evidence A II and a strong recommendation grade, according to the researcher's expertise. The critical commentary allowed us to conclude that vitamin D supplementation could improve hormonal components such as insulin resistance, hyperandrogenism, as well as metabolic components at the level of cholesterol and low-density lipoprotein (LDL), although additional research is required that complement the gaps and limitations that still exist in this field.
Acceso abierto
Revisión crítica: efecto de la suplementación con curcumina durante la quimioterapia / radioterapia en pacientes adultos con cáncer de cabeza y cuello
(Universidad Privada Norbert Wiener, 2024-11-06) Cabezas Quinto, Janet Chabeli; Bohórquez Medina, Andrea Lisbet
La curcumina es el compuesto activo de la planta medicinal cúrcuma, que pertenece a la familia Zingiberáceas y tiene su origen en Asia. Diversos estudios experimentales han determinado su potencial biológico y terapéutico, principalmente atribuyéndole propiedades antioxidantes, antiinflamatorias, antimoduladoras, hipolipemiantes y antineoplásicas. La presente revisión crítica tuvo como objetivo evaluar la efectividad de la suplementación con curcumina en relación con los desenlaces primarios (sintomatología asociada a la quimioterapia) y secundarios (potencial quimiopreventivo y terapéutico). Se aplicó la nutrición basada en evidencia (NuBE). Se llevó a cabo una búsqueda bibliográfica utilizando bases de datos científicas reconocidas, como Web of Science, Science Direct y PubMed. Se seleccionaron un total de 28 estudios clínicos, de los cuales se incluyeron únicamente 12 artículos (entre ensayos clínicos y revisiones sistemáticas) que cumplieron con los criterios de elegibilidad. Cada artículo fue evaluado de manera crítica utilizando la herramienta CASPE. Finalmente, se eligió un ensayo clínico aleatorizado titulado “Effects of nanomicelle curcumin capsules on prevention and treatment of oral mucositis in patients under chemotherapy with or without head and neck radiotherapy: a randomized clinical trial”. Se concluyó que la suplementación con curcumina es efectiva para reducir la sintomatología asociada a la quimioterapia y radioterapia en pacientes con cáncer de cabeza y cuello.