Examinando por Materia "Cystatin C"

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    Relationship Between Serum Cystatin C Levels and Endogenous Creatinine Clearance in Adult Patients with Chronic Kidney Disease Attended at the Nephrology Service of a Level III-2 Hospital in Lima, January - July 2017
    (Universidad Privada Norbert Wiener, 2018-06-19) Mestanza Jimenez, Nancy Del Rosario; Palomino Contreras, Mónica Alina; Arias Caycho, Luis Clever
    Objective: To determine the relationship between serum cystatin C levels and endogenous creatinine clearance in adult patients with chronic kidney disease (CKD) treated at the Nephrology service of a level III-2 hospital in Lima, from January to July 2017. Materials and Methods: This is a descriptive, retrospective, cross-sectional study involving 286 adult CKD patients treated at the Nephrology service of a level III-2 hospital in Lima, from January to July 2017. Results: The age ranged from 18 to 85 years, with a mean age of 43.2 years. The age group with the highest prevalence of CKD was between 31 to 50 years (118 patients). Of the total population, 156 were male and 130 were female. 251 participants had high cystatin C levels (> 0.95 mg/l), and 74.5% of the population had low endogenous creatinine clearance (<90 ml/min). Groups categorized by high cystatin C levels showed a significant inverse correlation (p=0.01) with the group classified by low endogenous creatinine clearance. The correlation between male sex and low endogenous creatinine clearance showed significant values (p=0.02), while no significance was found between age and endogenous creatinine clearance levels. Conclusion: There is an inverse relationship between serum cystatin C levels and endogenous creatinine clearance values in patients with CKD.