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Relationship of the immunophenotype by cytometry with the therapeutic evolution, in patients from 0 to 16 years with myeloid and lymphoid leukemia, of oncohematology of the carlos alberto seguin escobedo hospital, January 2016 - December 2020.
(Universidad Privada Norbert Wiener, 2021-12-11) Manrique Almenara, Gabriela Sofia; Ascarza Gallegos, Justo Angelo
Leukemias are a heterogeneous group of diseases characterized by the infiltration of neoplastic cells from the hematopoietic system into the bone marrow, blood, and other tissues. Studies show that leukemia is the most common malignancy in children, accounting for 30 to 38% of cancers in individuals under 15 years of age, with 75% being acute lymphoblastic leukemia and 20-25% being acute myeloblastic leukemia. Flow Cytometry Immunophenotyping is a technique used to indirectly study antigenic expressions of importance. The antibody panels used help identify normal maturation pathways, aiding in distinguishing these from abnormal ones seen in dysplastic processes. Furthermore, therapeutic evolution refers to how a disease is controlled with pharmacological or other treatments, with continuous monitoring of the treatment process.